Aerobic Exercise Facilitates the Nuclear Translocation of SREBP2 by Activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP/PS1 Mice

Impaired cholesterol synthesizing ability is considered a risk factor for the development of Alzheimer’s disease (AD), as evidenced by reduced levels of key proteases in the brain that mediate cholesterol synthesis; however, cholesterol deposition has been found in neurons in tangles in the brains o...

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Detalles Bibliográficos
Autores principales: Hu, Zelin, Yuan, Yangqi, Tong, Zhen, Liao, Meiqing, Yuan, Shunling, Wu, Weijia, Tang, Yingzhe, Wang, Yirong, Tang, Changfa, Liu, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454400/
https://www.ncbi.nlm.nih.gov/pubmed/37629027
http://dx.doi.org/10.3390/ijms241612847

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