Mechanistic Protective Effect of Cilostazol in Cisplatin-Induced Testicular Damage via Regulation of Oxidative Stress and TNF-α/NF-κB/Caspase-3 Pathways

Despite being a potent anticancer drug, cisplatin has limited applicability due to its adverse effects, such as testicular damage. Consequently, reducing its toxicity becomes necessary. In this study, a selective phosphodiesterase-3 inhibitor, cilostazol, which is used to treat intermittent claudica...

Descripción completa

Detalles Bibliográficos
Autores principales: Othman, Eman M., Habib, Heba A., Zahran, Mahmoud E., Amin, Amr, Heeba, Gehan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454637/
https://www.ncbi.nlm.nih.gov/pubmed/37628836
http://dx.doi.org/10.3390/ijms241612651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454637/
https://www.ncbi.nlm.nih.gov/pubmed/37628836
http://dx.doi.org/10.3390/ijms241612651

Ejemplares similares