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Examination of Factors Affecting Site-Directed RNA Editing by the MS2-ADAR1 Deaminase System

Adenosine deaminases acting on RNA (ADARs) have double-stranded RNA binding domains and a deaminase domain (DD). We used the MS2 system and specific guide RNAs to direct ADAR1-DD to target adenosines in the mRNA encoding-enhanced green fluorescence protein. Using this system in transfected HEK-293 c...

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Detalles Bibliográficos
Autores principales:	Azad, Md Thoufic Anam, Qulsum, Umme, Tsukahara, Toshifumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454654/ https://www.ncbi.nlm.nih.gov/pubmed/37628635 http://dx.doi.org/10.3390/genes14081584

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