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ATRX Loss in the Development and Prognosis of Conjunctival Melanoma

Metastatic disease is linked to TERT promoter mutations in conjunctival melanomas (CM). Both TERT promoter and ATRX mutations are associated with faulty telomere maintenance. This study aimed to determine the prognostic value of ATRX loss in conjunctival melanocytic lesions. Eighty-six conjunctival...

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Detalles Bibliográficos
Autores principales: van Ipenburg, Jolique A., van den Bosch, Quincy C. C., Paridaens, Dion, Dubbink, Hendrikus J., Kiliç, Emine, Naus, Nicole, Verdijk, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454703/
https://www.ncbi.nlm.nih.gov/pubmed/37629169
http://dx.doi.org/10.3390/ijms241612988