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Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries

Peripheral nerve injuries are common neurological disorders, and the available treatment options, such as conservative management and surgical repair, often yield limited results. However, there is growing interest in the potential of using chitosan-based biopolymers as a novel therapeutic approach...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, An, Heng, Zhang, Fengshi, Jiang, Haoran, Wan, Teng, Wen, Yongqiang, Han, Na, Zhang, Peixun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454829/
https://www.ncbi.nlm.nih.gov/pubmed/37629137
http://dx.doi.org/10.3390/ijms241612956
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author Zhang, Meng
An, Heng
Zhang, Fengshi
Jiang, Haoran
Wan, Teng
Wen, Yongqiang
Han, Na
Zhang, Peixun
author_facet Zhang, Meng
An, Heng
Zhang, Fengshi
Jiang, Haoran
Wan, Teng
Wen, Yongqiang
Han, Na
Zhang, Peixun
author_sort Zhang, Meng
collection PubMed
description Peripheral nerve injuries are common neurological disorders, and the available treatment options, such as conservative management and surgical repair, often yield limited results. However, there is growing interest in the potential of using chitosan-based biopolymers as a novel therapeutic approach to treating these injuries. Chitosan-based biopolymers possess unique characteristics, including biocompatibility, biodegradability, and the ability to stimulate cell proliferation, making them highly suitable for repairing nerve defects and promoting nerve regeneration and functional recovery. Furthermore, these biopolymers can be utilized in drug delivery systems to control the release of therapeutic agents and facilitate the growth of nerve cells. This comprehensive review focuses on the latest advancements in utilizing chitosan-based biopolymers for peripheral nerve regeneration. By harnessing the potential of chitosan-based biopolymers, we can pave the way for innovative treatment strategies that significantly improve the outcomes of peripheral nerve injury repair, offering renewed hope and better prospects for patients in need.
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spelling pubmed-104548292023-08-26 Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries Zhang, Meng An, Heng Zhang, Fengshi Jiang, Haoran Wan, Teng Wen, Yongqiang Han, Na Zhang, Peixun Int J Mol Sci Review Peripheral nerve injuries are common neurological disorders, and the available treatment options, such as conservative management and surgical repair, often yield limited results. However, there is growing interest in the potential of using chitosan-based biopolymers as a novel therapeutic approach to treating these injuries. Chitosan-based biopolymers possess unique characteristics, including biocompatibility, biodegradability, and the ability to stimulate cell proliferation, making them highly suitable for repairing nerve defects and promoting nerve regeneration and functional recovery. Furthermore, these biopolymers can be utilized in drug delivery systems to control the release of therapeutic agents and facilitate the growth of nerve cells. This comprehensive review focuses on the latest advancements in utilizing chitosan-based biopolymers for peripheral nerve regeneration. By harnessing the potential of chitosan-based biopolymers, we can pave the way for innovative treatment strategies that significantly improve the outcomes of peripheral nerve injury repair, offering renewed hope and better prospects for patients in need. MDPI 2023-08-19 /pmc/articles/PMC10454829/ /pubmed/37629137 http://dx.doi.org/10.3390/ijms241612956 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Meng
An, Heng
Zhang, Fengshi
Jiang, Haoran
Wan, Teng
Wen, Yongqiang
Han, Na
Zhang, Peixun
Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries
title Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries
title_full Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries
title_fullStr Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries
title_full_unstemmed Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries
title_short Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries
title_sort prospects of using chitosan-based biopolymers in the treatment of peripheral nerve injuries
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454829/
https://www.ncbi.nlm.nih.gov/pubmed/37629137
http://dx.doi.org/10.3390/ijms241612956
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