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miR-143-3p Promotes Ovarian Granulosa Cell Senescence and Inhibits Estradiol Synthesis by Targeting UBE2E3 and LHCGR

The ovary is a highly susceptible organ to senescence, and granulosa cells (GCs) have a crucial role in oocyte development promotion and overall ovarian function maintenance. As age advances, GCs apoptosis and dysfunction escalate, leading to ovarian aging. However, the molecular mechanisms underpin...

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Detalles Bibliográficos
Autores principales:	Deng, Jingxian, Tang, Yan, Li, Lu, Huang, Rufei, Wang, Zhaoyang, Ye, Tao, Xiao, Ziyan, Hu, Meirong, Wei, Siying, Wang, Yuxin, Yang, Yan, Huang, Yadong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454865/ https://www.ncbi.nlm.nih.gov/pubmed/37628741 http://dx.doi.org/10.3390/ijms241612560

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