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miR-143-3p Promotes Ovarian Granulosa Cell Senescence and Inhibits Estradiol Synthesis by Targeting UBE2E3 and LHCGR
The ovary is a highly susceptible organ to senescence, and granulosa cells (GCs) have a crucial role in oocyte development promotion and overall ovarian function maintenance. As age advances, GCs apoptosis and dysfunction escalate, leading to ovarian aging. However, the molecular mechanisms underpin...
Autores principales: | Deng, Jingxian, Tang, Yan, Li, Lu, Huang, Rufei, Wang, Zhaoyang, Ye, Tao, Xiao, Ziyan, Hu, Meirong, Wei, Siying, Wang, Yuxin, Yang, Yan, Huang, Yadong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454865/ https://www.ncbi.nlm.nih.gov/pubmed/37628741 http://dx.doi.org/10.3390/ijms241612560 |
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