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A Comparative Study of a Small Series of Patients (50 Patients) with Pelvic Varicose Veins Treated with Plugs Alone or Plugs and Polidocanol
Level of Evidence: Level 2. Purpose: To compare the safety and efficacy of vascular plug (VP) and vascular plug and polidocanol foam (VPPF) treatments for embolization in pelvic congestion syndrome (PCS). Materials and methods: A comparative, prospective, two-center study enrolled 50 women with PCS...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455180/ https://www.ncbi.nlm.nih.gov/pubmed/37629450 http://dx.doi.org/10.3390/jcm12165408 |
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author | De Gregorio, Miguel Ángel Yamamoto-Ramos, Masao Fredes, Arturo Serrano-Casorran, Carolina Sierre, Sergio Ciampi-Dopazo, Juan José Méndez, Santiago Abadal, Jose Maria Urtiaga, Ignacio Bonastre, Cristina Rodríguez, Jose Urbano, Jose Guirola, José Andrés |
author_facet | De Gregorio, Miguel Ángel Yamamoto-Ramos, Masao Fredes, Arturo Serrano-Casorran, Carolina Sierre, Sergio Ciampi-Dopazo, Juan José Méndez, Santiago Abadal, Jose Maria Urtiaga, Ignacio Bonastre, Cristina Rodríguez, Jose Urbano, Jose Guirola, José Andrés |
author_sort | De Gregorio, Miguel Ángel |
collection | PubMed |
description | Level of Evidence: Level 2. Purpose: To compare the safety and efficacy of vascular plug (VP) and vascular plug and polidocanol foam (VPPF) treatments for embolization in pelvic congestion syndrome (PCS). Materials and methods: A comparative, prospective, two-center study enrolled 50 women with PCS from January 2019 to January 2020. The patients were divided into two groups, and embolization was performed with VP (n = 25) and VPPF (n = 25) treatments. The mean age of the patients was 45.6 years ± 6.9. Three clinical parameters were assessed: abdominal pain, dyspareunia, and lower limb pain. The primary outcome (clinical success at 1 yr using a VAS), number of devices, procedure and fluoroscopy times, radiation doses, costs, and complications were compared. The participants were followed-up at 1, 3, 6, and 12 months. Results: At the 1-year follow-up, clinical success did not significantly differ between the two groups (VP vs. VPPF) regarding the improvement of the symptoms analyzed (pelvic pain, dyspareunia, lower extremity pain, and other symptoms (p < 0.05)). The mean number of devices per case was 4 ± 1.1 for the VP group and 2 ± 0.31 for the VPPF group (p < 0.001). No major complications were recorded in either group. The VPPF group had a significantly longer fluoroscopy time (42.8 min ± 14.2 vs. 25.4 min ± 7) and longer radiation dose (VPPF air kerma 839.4 ± 513 vs. VP air kerma 658.4 mGy ± 355 (all p < 0.001)). Conclusions: Embolization for PCS resulted in pain relief in 90% of patients; the use of polidocanol did not demonstrate changes in the clinical outcome. The use of a VP alone was associated with decreased fluoroscopy time and radiation dose. |
format | Online Article Text |
id | pubmed-10455180 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104551802023-08-26 A Comparative Study of a Small Series of Patients (50 Patients) with Pelvic Varicose Veins Treated with Plugs Alone or Plugs and Polidocanol De Gregorio, Miguel Ángel Yamamoto-Ramos, Masao Fredes, Arturo Serrano-Casorran, Carolina Sierre, Sergio Ciampi-Dopazo, Juan José Méndez, Santiago Abadal, Jose Maria Urtiaga, Ignacio Bonastre, Cristina Rodríguez, Jose Urbano, Jose Guirola, José Andrés J Clin Med Article Level of Evidence: Level 2. Purpose: To compare the safety and efficacy of vascular plug (VP) and vascular plug and polidocanol foam (VPPF) treatments for embolization in pelvic congestion syndrome (PCS). Materials and methods: A comparative, prospective, two-center study enrolled 50 women with PCS from January 2019 to January 2020. The patients were divided into two groups, and embolization was performed with VP (n = 25) and VPPF (n = 25) treatments. The mean age of the patients was 45.6 years ± 6.9. Three clinical parameters were assessed: abdominal pain, dyspareunia, and lower limb pain. The primary outcome (clinical success at 1 yr using a VAS), number of devices, procedure and fluoroscopy times, radiation doses, costs, and complications were compared. The participants were followed-up at 1, 3, 6, and 12 months. Results: At the 1-year follow-up, clinical success did not significantly differ between the two groups (VP vs. VPPF) regarding the improvement of the symptoms analyzed (pelvic pain, dyspareunia, lower extremity pain, and other symptoms (p < 0.05)). The mean number of devices per case was 4 ± 1.1 for the VP group and 2 ± 0.31 for the VPPF group (p < 0.001). No major complications were recorded in either group. The VPPF group had a significantly longer fluoroscopy time (42.8 min ± 14.2 vs. 25.4 min ± 7) and longer radiation dose (VPPF air kerma 839.4 ± 513 vs. VP air kerma 658.4 mGy ± 355 (all p < 0.001)). Conclusions: Embolization for PCS resulted in pain relief in 90% of patients; the use of polidocanol did not demonstrate changes in the clinical outcome. The use of a VP alone was associated with decreased fluoroscopy time and radiation dose. MDPI 2023-08-20 /pmc/articles/PMC10455180/ /pubmed/37629450 http://dx.doi.org/10.3390/jcm12165408 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article De Gregorio, Miguel Ángel Yamamoto-Ramos, Masao Fredes, Arturo Serrano-Casorran, Carolina Sierre, Sergio Ciampi-Dopazo, Juan José Méndez, Santiago Abadal, Jose Maria Urtiaga, Ignacio Bonastre, Cristina Rodríguez, Jose Urbano, Jose Guirola, José Andrés A Comparative Study of a Small Series of Patients (50 Patients) with Pelvic Varicose Veins Treated with Plugs Alone or Plugs and Polidocanol |
title | A Comparative Study of a Small Series of Patients (50 Patients) with Pelvic Varicose Veins Treated with Plugs Alone or Plugs and Polidocanol |
title_full | A Comparative Study of a Small Series of Patients (50 Patients) with Pelvic Varicose Veins Treated with Plugs Alone or Plugs and Polidocanol |
title_fullStr | A Comparative Study of a Small Series of Patients (50 Patients) with Pelvic Varicose Veins Treated with Plugs Alone or Plugs and Polidocanol |
title_full_unstemmed | A Comparative Study of a Small Series of Patients (50 Patients) with Pelvic Varicose Veins Treated with Plugs Alone or Plugs and Polidocanol |
title_short | A Comparative Study of a Small Series of Patients (50 Patients) with Pelvic Varicose Veins Treated with Plugs Alone or Plugs and Polidocanol |
title_sort | comparative study of a small series of patients (50 patients) with pelvic varicose veins treated with plugs alone or plugs and polidocanol |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455180/ https://www.ncbi.nlm.nih.gov/pubmed/37629450 http://dx.doi.org/10.3390/jcm12165408 |
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