Cargando…

Copy Number Variations and Gene Mutations Identified by Multiplex Ligation-Dependent Probe Amplification in Romanian Chronic Lymphocytic Leukemia Patients

Chronic lymphocytic leukemia (CLL) is known for its wide-ranging clinical and genetic diversity. The study aimed to assess the associations between copy number variations (CNVs) and various biological and clinical features, as well as the survival rates of CLL patients and to evaluate the effectiven...

Descripción completa

Detalles Bibliográficos
Autores principales:	Balla, Beata, Tripon, Florin, Candea, Marcela, Banescu, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455273/ https://www.ncbi.nlm.nih.gov/pubmed/37623489 http://dx.doi.org/10.3390/jpm13081239

Ejemplares similares

From Descriptive to Functional Genomics of Leukemias Focusing on Genome Engineering Techniques
por: Balla, Beata, et al.
Publicado: (2021)

Rapid Identification of Key Copy Number Alterations in B- and T-Cell Acute Lymphoblastic Leukemia by Digital Multiplex Ligation-Dependent Probe Amplification
por: Thakral, Deepshi, et al.
Publicado: (2019)

Multiplex ligation-dependent probe amplification identifies copy number changes in normal and undetectable karyotype MDS patients
por: Ma, Jing, et al.
Publicado: (2021)

Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (MLPA)
por: González, Juan R, et al.
Publicado: (2008)

Analysis of gene copy number variations in patients with congenital heart disease using multiplex ligation-dependent probe amplification
por: Mutlu, Esra Tuba, et al.
Publicado: (2018)

Assessment of p53 and ATM functionality in chronic lymphocytic leukemia by multiplex ligation-dependent probe amplification
por: te Raa, G D, et al.
Publicado: (2015)

Association Analysis of TP53 rs1042522, MDM2 rs2279744, rs3730485, MDM4 rs4245739 Variants and Acute Myeloid Leukemia Susceptibility, Risk Stratification Scores, and Clinical Features: An Exploratory Study
por: Tripon, Florin, et al.
Publicado: (2020)

Multiplex Ligation-Dependent Probe Amplification Analysis of GATA4 Gene Copy Number Variations in Patients with Isolated Congenital Heart Disease
por: Guida, Valentina, et al.
Publicado: (2010)

Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia
por: Bashton, Matthew, et al.
Publicado: (2020)

Quantitative copy number analysis by Multiplex Ligation-dependent Probe Amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness
por: Lips, Esther H, et al.
Publicado: (2011)

Analysis of chromosome 22q11 copy number variations by multiplex ligation-dependent probe amplification for prenatal diagnosis of congenital heart defect
por: Zhang, Jingjing, et al.
Publicado: (2015)

Alterations of Copy Number of Methylation Pattern in Mismatch Repair Genes by Methylation Specific-Multiplex Ligation-Dependent Probe Amplification in Cases of Colon Cancer
por: Onrat, ST, et al.
Publicado: (2011)

FTO rs 9939609 SNP Is Associated With Adiponectin and Leptin Levels and the Risk of Obesity in a Cohort of Romanian Children Population
por: Duicu, Carmen, et al.
Publicado: (2016)

Oncogene amplification in male breast cancer: analysis by multiplex ligation-dependent probe amplification
por: Kornegoor, Robert, et al.
Publicado: (2012)

The Genetic Landscape of Myelodysplastic Neoplasm Progression to Acute Myeloid Leukemia
por: Bănescu, Claudia, et al.
Publicado: (2023)

A modified multiplex ligation-dependent probe amplification method for the detection of 22q11.2 copy number variations in patients with congenital heart disease
por: Zhang, Xiaoqing, et al.
Publicado: (2015)

Next-generation sequencing verified by multiplex ligation-dependent probe amplification to detect a new copy number variations in a child with heterozygous familial hypercholesterolemia
por: Yan, Hui, et al.
Publicado: (2021)

Detection, Analysis and Clinical Validation of Chromosomal Aberrations by Multiplex Ligation-Dependent Probe Amplification in Chronic Leukemia
por: Abdool, Adam, et al.
Publicado: (2010)

MAPD: a probe design suite for multiplex ligation-dependent probe amplification assays
por: Zhi, Jizu
Publicado: (2010)

Comprehensive chronic lymphocytic leukemia diagnostics by combined multiplex ligation dependent probe amplification (MLPA) and interphase fluorescence in situ hybridization (iFISH)
por: Alhourani, Eyad, et al.
Publicado: (2014)

From Six Gene Polymorphisms of the Antioxidant System, Only GPX Pro198Leu and GSTP1 Ile105Val Modulate the Risk of Acute Myeloid Leukemia
por: Bănescu, Claudia, et al.
Publicado: (2016)

Association of TLR4 Rs4986791 Polymorphism and TLR9 Haplotypes with Acute Myeloid Leukemia Susceptibility: A Case-Control Study of Adult Patients
por: Banescu, Claudia, et al.
Publicado: (2022)

Dosage analysis of cancer predisposition genes by multiplex ligation-dependent probe amplification
por: Bunyan, D J, et al.
Publicado: (2004)

Application of Chromosomal Microarray and Multiplex Ligation-dependent Probe Amplification in prenatal diagnosis
por: Sharma, Pankaj, et al.
Publicado: (2014)

Cluster analysis of multiplex ligation-dependent probe amplification data in choroidal melanoma
por: Caines, Rhydian, et al.
Publicado: (2015)

Application of multiplex ligation-dependent probe amplification in the genetic testing of oculocutaneous albinism
por: Zhang, Ying-Zi, et al.
Publicado: (2019)

Multiplex ligation-dependent probe amplification assay identifies additional copy number changes compared with R-band karyotype and provide more accuracy prognostic information in myelodysplastic syndromes
por: Wang, Jingya, et al.
Publicado: (2016)

Genetic screening method for analyzing survival motor neuron copy number in spinal muscular atrophy by multiplex ligation-dependent probe amplification and droplet digital polymerase chain reaction
por: Hong, Jing-Mei, et al.
Publicado: (2020)

Cytokine rs361525, rs1800750, rs1800629, rs1800896, rs1800872, rs1800795, rs1800470, and rs2430561 SNPs in relation with prognostic factors in acute myeloid leukemia
por: Bănescu, Claudia, et al.
Publicado: (2019)

A novel study of Copy Number Variations in Hirschsprung disease using the Multiple Ligation-dependent Probe Amplification (MLPA) technique
por: Núñez-Torres, Rocío, et al.
Publicado: (2009)

Impact of demographic, genetic, and bioimpedance factors on gestational weight gain and birth weight in a Romanian population: A cross-sectional study in mothers and their newborns: the Monebo study (STROBE-compliant article)
por: Mărginean, Claudiu, et al.
Publicado: (2016)

Rapid Analysis of Saccharomyces cerevisiae Genome Rearrangements by Multiplex Ligation–Dependent Probe Amplification
por: Chan, Jason E., et al.
Publicado: (2012)

Promoter hypermethylation in male breast cancer: analysis by multiplex ligation-dependent probe amplification
por: Kornegoor, Robert, et al.
Publicado: (2012)

Three Cases of False-positive Multiplex Ligation-dependent Probe Amplification of BRCA1
por: Kim, Kyoung Bo, et al.
Publicado: (2022)

Added Value of HER-2 Amplification Testing by Multiplex Ligation-Dependent Probe Amplification in Invasive Breast Cancer
por: Kuijpers, Chantal C. H. J., et al.
Publicado: (2013)

Multiplex ligation-dependent probe amplification (MLPA) enhances the molecular diagnosis of aniridia and related disorders
por: Redeker, Egbert J.W., et al.
Publicado: (2008)

Can we rely on the multiplex ligation-dependent probe amplification method (MLPA) for prenatal diagnosis?
por: Omrani, Mir Davood, et al.
Publicado: (2014)

Multiplex ligation-dependant probe amplification study of children with idiopathic mental retardation in South India
por: John, Neetha, et al.
Publicado: (2013)

Multiplex Ligation-Dependent Probe Amplification in X-linked Recessive Muscular Dystrophy in Korean Subjects
por: Suh, Mi Ri, et al.
Publicado: (2017)

A simple way to evaluate self-designed probes for tumor specific Multiplex Ligation-dependent Probe Amplification (MLPA)
por: Pedersen, Kristina, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_319gd2p2d51nm2up8ltundlpi2