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Hospital Incidence, Treatment, and Outcome of 885 Patients with Thoracoabdominal Aortic Aneurysms Treated in Switzerland over 10 Years—A Secondary Analysis of Swiss DRG Data

Despite the development of fenestrated and branched endovascular aortic repair (f/bEVAR), the surgical management of thoraco-abdominal aortic aneurysms (TAAAs) remains a major challenge. The aim of this study was to analyse the hospital incidence and hospital mortality of patients treated for TAAAs...

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Autores principales: Stoklasa, Kerstin, Menges, Anna-Leonie, Reutersberg, Benedikt, Meuli, Lorenz, Zimmermann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455290/
https://www.ncbi.nlm.nih.gov/pubmed/37629255
http://dx.doi.org/10.3390/jcm12165213
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author Stoklasa, Kerstin
Menges, Anna-Leonie
Reutersberg, Benedikt
Meuli, Lorenz
Zimmermann, Alexander
author_facet Stoklasa, Kerstin
Menges, Anna-Leonie
Reutersberg, Benedikt
Meuli, Lorenz
Zimmermann, Alexander
author_sort Stoklasa, Kerstin
collection PubMed
description Despite the development of fenestrated and branched endovascular aortic repair (f/bEVAR), the surgical management of thoraco-abdominal aortic aneurysms (TAAAs) remains a major challenge. The aim of this study was to analyse the hospital incidence and hospital mortality of patients treated for TAAAs in Switzerland. Secondary data analysis was performed using nationwide administrative discharge data from 2009–2018. Standardised incidence rates and adjusted mortality rates were calculated. A total of 885 cases were identified (83.2% nonruptured (nrTAAA), 16.8% ruptured (rTAAA)), where 69.3% were male. The hospital incidence rate for nrTAAA was 0.4 per 100,000 women and 0.9 per 100,000 men in 2009, which had doubled for both sexes by 2018. For rTAAA, there was no trend over the years. The most common procedure was f/bEVAR (44.2%), followed by OAR (39.5%), and 9.8% received a hybrid procedure. There was a significant increase in endovascular procedures over time. The all-cause mortality was 7.1% with nrTAAA and 55% with rTAAA. The mortality was lower for rTAAA when f/bEVAR or hybrid procedures were used. A ruptured aneurysm and higher comorbidity were associated with higher hospital mortality. This study demonstrates that the treatment approach has changed significantly over the observed period. The use of f/bEVAR nearly tripled in nrTAAA and doubled in rTAAA during this decade.
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spelling pubmed-104552902023-08-26 Hospital Incidence, Treatment, and Outcome of 885 Patients with Thoracoabdominal Aortic Aneurysms Treated in Switzerland over 10 Years—A Secondary Analysis of Swiss DRG Data Stoklasa, Kerstin Menges, Anna-Leonie Reutersberg, Benedikt Meuli, Lorenz Zimmermann, Alexander J Clin Med Article Despite the development of fenestrated and branched endovascular aortic repair (f/bEVAR), the surgical management of thoraco-abdominal aortic aneurysms (TAAAs) remains a major challenge. The aim of this study was to analyse the hospital incidence and hospital mortality of patients treated for TAAAs in Switzerland. Secondary data analysis was performed using nationwide administrative discharge data from 2009–2018. Standardised incidence rates and adjusted mortality rates were calculated. A total of 885 cases were identified (83.2% nonruptured (nrTAAA), 16.8% ruptured (rTAAA)), where 69.3% were male. The hospital incidence rate for nrTAAA was 0.4 per 100,000 women and 0.9 per 100,000 men in 2009, which had doubled for both sexes by 2018. For rTAAA, there was no trend over the years. The most common procedure was f/bEVAR (44.2%), followed by OAR (39.5%), and 9.8% received a hybrid procedure. There was a significant increase in endovascular procedures over time. The all-cause mortality was 7.1% with nrTAAA and 55% with rTAAA. The mortality was lower for rTAAA when f/bEVAR or hybrid procedures were used. A ruptured aneurysm and higher comorbidity were associated with higher hospital mortality. This study demonstrates that the treatment approach has changed significantly over the observed period. The use of f/bEVAR nearly tripled in nrTAAA and doubled in rTAAA during this decade. MDPI 2023-08-10 /pmc/articles/PMC10455290/ /pubmed/37629255 http://dx.doi.org/10.3390/jcm12165213 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Stoklasa, Kerstin
Menges, Anna-Leonie
Reutersberg, Benedikt
Meuli, Lorenz
Zimmermann, Alexander
Hospital Incidence, Treatment, and Outcome of 885 Patients with Thoracoabdominal Aortic Aneurysms Treated in Switzerland over 10 Years—A Secondary Analysis of Swiss DRG Data
title Hospital Incidence, Treatment, and Outcome of 885 Patients with Thoracoabdominal Aortic Aneurysms Treated in Switzerland over 10 Years—A Secondary Analysis of Swiss DRG Data
title_full Hospital Incidence, Treatment, and Outcome of 885 Patients with Thoracoabdominal Aortic Aneurysms Treated in Switzerland over 10 Years—A Secondary Analysis of Swiss DRG Data
title_fullStr Hospital Incidence, Treatment, and Outcome of 885 Patients with Thoracoabdominal Aortic Aneurysms Treated in Switzerland over 10 Years—A Secondary Analysis of Swiss DRG Data
title_full_unstemmed Hospital Incidence, Treatment, and Outcome of 885 Patients with Thoracoabdominal Aortic Aneurysms Treated in Switzerland over 10 Years—A Secondary Analysis of Swiss DRG Data
title_short Hospital Incidence, Treatment, and Outcome of 885 Patients with Thoracoabdominal Aortic Aneurysms Treated in Switzerland over 10 Years—A Secondary Analysis of Swiss DRG Data
title_sort hospital incidence, treatment, and outcome of 885 patients with thoracoabdominal aortic aneurysms treated in switzerland over 10 years—a secondary analysis of swiss drg data
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455290/
https://www.ncbi.nlm.nih.gov/pubmed/37629255
http://dx.doi.org/10.3390/jcm12165213
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