Cargando…

Cleavage and Polyadenylation-Specific Factor 4 (CPSF4) Expression Is Associated with Enhanced Prostate Cancer Cell Migration and Cell Cycle Dysregulation, In Vitro

Potential oncogene cleavage and polyadenylation specific factor 4 (CPSF4) has been linked to several cancer types. However, little research has been conducted on its function in prostate cancer (PCa). In benign, incidental, advanced, and castrate resistant PCa (CRPCa) patient samples, protein expres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choudhry, Muhammad, Gamallat, Yaser, Ghosh, Sunita, Bismar, Tarek A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455462/ https://www.ncbi.nlm.nih.gov/pubmed/37629142 http://dx.doi.org/10.3390/ijms241612961

Ejemplares similares

Downregulation of BUD31 Promotes Prostate Cancer Cell Proliferation and Migration via Activation of p-AKT and Vimentin In Vitro
por: Choudhry, Muhammad, et al.
Publicado: (2023)

Glycyl-tRNA Synthetase (GARS) Expression Is Associated with Prostate Cancer Progression and Its Inhibition Decreases Migration, and Invasion In Vitro
por: Khosh Kish, Ealia, et al.
Publicado: (2023)

ARPC1B Is Associated with Lethal Prostate Cancer and Its Inhibition Decreases Cell Invasion and Migration In Vitro
por: Gamallat, Yaser, et al.
Publicado: (2022)

Editorial: The Application of Proteogenomics to Urine Analysis for the Identification of Novel Biomarkers of Prostate Cancer: An Exploratory Study
por: Gamallat, Yaser, et al.
Publicado: (2023)

Serrate RNA Effector Molecule (SRRT) Is Associated with Prostate Cancer Progression and Is a Predictor of Poor Prognosis in Lethal Prostate Cancer
por: Gamallat, Yaser, et al.
Publicado: (2023)

Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33
por: Schönemann, Lars, et al.
Publicado: (2014)

The Expression of Proto-Oncogene ETS-Related Gene (ERG) Plays a Central Role in the Oncogenic Mechanism Involved in the Development and Progression of Prostate Cancer
por: Khosh Kish, Ealia, et al.
Publicado: (2022)

The Association between Cyclin Dependent Kinase 2 Associated Protein 1 (CDK2AP1) and Molecular Subtypes of Lethal Prostate Cancer
por: Gamallat, Yaser, et al.
Publicado: (2022)

Distinctive interactions of the Arabidopsis homolog of the 30 kD subunit of the cleavage and polyadenylation specificity factor (AtCPSF30) with other polyadenylation factor subunits
por: Rao, Suryadevara, et al.
Publicado: (2009)

CPSF30 at the Interface of Alternative Polyadenylation and Cellular Signaling in Plants
por: Chakrabarti, Manohar, et al.
Publicado: (2015)

CPSF6 links alternative polyadenylation to metabolism adaption in hepatocellular carcinoma progression
por: Tan, Sheng, et al.
Publicado: (2021)

Alternative polyadenylation factor CPSF6 regulates temperature compensation of the mammalian circadian clock
por: Schmal, Christoph, et al.
Publicado: (2023)

Alternative polyadenylation factors link cell cycle to migration
por: Mitra, Mithun, et al.
Publicado: (2018)

Suppression of CPSF6 Enhances Apoptosis Through Alternative Polyadenylation-Mediated Shortening of the VHL 3′UTR in Gastric Cancer Cells
por: Shi, Xinglong, et al.
Publicado: (2021)

Mutation in cpsf6/CFIm68 (Cleavage and Polyadenylation Specificity Factor Subunit 6) causes short 3'UTRs and disturbs gene expression in developing embryos, as revealed by an analysis of primordial germ cell migration using the medaka mutant naruto
por: Sasado, Takao, et al.
Publicado: (2017)

Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6
por: Jang, Sooin, et al.
Publicado: (2019)

Epidermal progenitors suppress GRHL3-mediated differentiation through intronic polyadenylation promoted by CPSF-HNRNPA3 collaboration
por: Chen, Xin, et al.
Publicado: (2021)

Large, Nested Variant of Urothelial Carcinoma Is Enriched with Activating Mutations in Fibroblast Growth Factor Receptor-3 among Other Targetable Mutations
por: Gamallat, Yaser, et al.
Publicado: (2023)

Transcriptional activity regulates alternative cleavage and polyadenylation
por: Ji, Zhe, et al.
Publicado: (2011)

CPSF4 promotes triple negative breast cancer metastasis by upregulating MDM4
por: Lee, Kaping, et al.
Publicado: (2021)

Upregulation of Cleavage and Polyadenylation Specific Factor 4 in Lung Adenocarcinoma and Its Critical Role for Cancer Cell Survival and Proliferation
por: Chen, Wangbing, et al.
Publicado: (2013)

THOC5 controls 3′end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100)
por: Tran, Doan Duy Hai, et al.
Publicado: (2014)

Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin
por: Thore, Stéphane, et al.
Publicado: (2023)

Cleavage and polyadenylation: Ending the message expands gene regulation
por: Neve, Jonathan, et al.
Publicado: (2017)

Comprehensive analysis of CPSF4-related alternative splice genes in hepatocellular carcinoma
por: Yuemaierabola, Anwaier, et al.
Publicado: (2023)

Archaeal β-CASP ribonucleases of the aCPSF1 family are orthologs of the eukaryal CPSF-73 factor
por: Phung, Duy Khanh, et al.
Publicado: (2013)

Requirement for cleavage factor II(m) in the control of alternative polyadenylation in breast cancer cells
por: Turner, Rachael E., et al.
Publicado: (2020)

Cell Cycle Regulation by Alternative Polyadenylation of CCND1
por: Wang, Qiong, et al.
Publicado: (2018)

A compendium of conserved cleavage and polyadenylation events in mammalian genes
por: Wang, Ruijia, et al.
Publicado: (2018)

Cleavage and Polyadenylation Specific Factor 1 Promotes Tumor Progression via Alternative Polyadenylation and Splicing in Hepatocellular Carcinoma
por: Chen, Shi-lu, et al.
Publicado: (2021)

Targeting the mRNA endonuclease CPSF73 inhibits breast cancer cell migration, invasion, and self-renewal
por: Liu, Huiyun, et al.
Publicado: (2022)

A comprehensive analysis of 3′ end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and polyadenylation
por: Gruber, Andreas J., et al.
Publicado: (2016)

CPSF6 is a Clinically Relevant Breast Cancer Vulnerability Target: Role of CPSF6 in Breast Cancer
por: Binothman, Najat, et al.
Publicado: (2017)

Analysis of alterative cleavage and polyadenylation by 3′ region extraction and deep sequencing
por: Hoque, Mainul, et al.
Publicado: (2012)

Direct Sequencing of Arabidopsis thaliana RNA Reveals Patterns of Cleavage and Polyadenylation
por: Sherstnev, Alexander, et al.
Publicado: (2012)

hnRNPC regulates cancer-specific alternative cleavage and polyadenylation profiles
por: Fischl, Harry, et al.
Publicado: (2019)

Formation of nuclear CPSF6/CPSF5 biomolecular condensates upon HIV-1 entry into the nucleus is important for productive infection
por: Luchsinger, Charlotte, et al.
Publicado: (2023)

The conserved ribonuclease aCPSF1 triggers genome-wide transcription termination of Archaea via a 3′-end cleavage mode
por: Yue, Lei, et al.
Publicado: (2020)

Silencing of CPSF7 inhibits the proliferation, migration, and invasion of lung adenocarcinoma cells by blocking the AKT/mTOR signaling pathway
por: An, Weishao, et al.
Publicado: (2022)

Alternative cleavage and polyadenylation in spermatogenesis connects chromatin regulation with post-transcriptional control
por: Li, Wencheng, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_n2d24vb8lcsortvn4hbobaee2j