Cardiomyocyte-Restricted Expression of IL11 Causes Cardiac Fibrosis, Inflammation, and Dysfunction

Cardiac fibrosis is a common pathological process in heart disease, representing a therapeutic target. Transforming growth factor β (TGFβ) is the canonical driver of cardiac fibrosis and was recently shown to be dependent on interleukin 11 (IL11) for its profibrotic effects in fibroblasts. In the op...

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Detalles Bibliográficos
Autores principales: Sweeney, Mark, O’Fee, Katie, Villanueva-Hayes, Chelsie, Rahman, Ekhlas, Lee, Michael, Vanezis, Konstantinos, Andrew, Ivan, Lim, Wei-Wen, Widjaja, Anissa, Barton, Paul J. R., Cook, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455677/
https://www.ncbi.nlm.nih.gov/pubmed/37629170
http://dx.doi.org/10.3390/ijms241612989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455677/
https://www.ncbi.nlm.nih.gov/pubmed/37629170
http://dx.doi.org/10.3390/ijms241612989

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