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Public Health Research Priorities for Fungal Diseases: A Multidisciplinary Approach to Save Lives

Fungal infections can cause severe disease and death and impose a substantial economic burden on healthcare systems. Public health research requires a multidisciplinary approach and is essential to help save lives and prevent disability from fungal diseases. In this manuscript, we outline the main p...

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Autores principales: Smith, Dallas J., Gold, Jeremy A. W., Benedict, Kaitlin, Wu, Karen, Lyman, Meghan, Jordan, Alexander, Medina, Narda, Lockhart, Shawn R., Sexton, D. Joseph, Chow, Nancy A., Jackson, Brendan R., Litvintseva, Anastasia P., Toda, Mitsuru, Chiller, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455901/
https://www.ncbi.nlm.nih.gov/pubmed/37623591
http://dx.doi.org/10.3390/jof9080820
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author Smith, Dallas J.
Gold, Jeremy A. W.
Benedict, Kaitlin
Wu, Karen
Lyman, Meghan
Jordan, Alexander
Medina, Narda
Lockhart, Shawn R.
Sexton, D. Joseph
Chow, Nancy A.
Jackson, Brendan R.
Litvintseva, Anastasia P.
Toda, Mitsuru
Chiller, Tom
author_facet Smith, Dallas J.
Gold, Jeremy A. W.
Benedict, Kaitlin
Wu, Karen
Lyman, Meghan
Jordan, Alexander
Medina, Narda
Lockhart, Shawn R.
Sexton, D. Joseph
Chow, Nancy A.
Jackson, Brendan R.
Litvintseva, Anastasia P.
Toda, Mitsuru
Chiller, Tom
author_sort Smith, Dallas J.
collection PubMed
description Fungal infections can cause severe disease and death and impose a substantial economic burden on healthcare systems. Public health research requires a multidisciplinary approach and is essential to help save lives and prevent disability from fungal diseases. In this manuscript, we outline the main public health research priorities for fungal diseases, including the measurement of the fungal disease burden and distribution and the need for improved diagnostics, therapeutics, and vaccines. Characterizing the public health, economic, health system, and individual burden caused by fungal diseases can provide critical insights to promote better prevention and treatment. The development and validation of fungal diagnostic tests that are rapid, accurate, and cost-effective can improve testing practices. Understanding best practices for antifungal prophylaxis can optimize prevention in at-risk populations, while research on antifungal resistance can improve patient outcomes. Investment in vaccines may eliminate certain fungal diseases or lower incidence and mortality. Public health research priorities and approaches may vary by fungal pathogen.
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spelling pubmed-104559012023-08-26 Public Health Research Priorities for Fungal Diseases: A Multidisciplinary Approach to Save Lives Smith, Dallas J. Gold, Jeremy A. W. Benedict, Kaitlin Wu, Karen Lyman, Meghan Jordan, Alexander Medina, Narda Lockhart, Shawn R. Sexton, D. Joseph Chow, Nancy A. Jackson, Brendan R. Litvintseva, Anastasia P. Toda, Mitsuru Chiller, Tom J Fungi (Basel) Review Fungal infections can cause severe disease and death and impose a substantial economic burden on healthcare systems. Public health research requires a multidisciplinary approach and is essential to help save lives and prevent disability from fungal diseases. In this manuscript, we outline the main public health research priorities for fungal diseases, including the measurement of the fungal disease burden and distribution and the need for improved diagnostics, therapeutics, and vaccines. Characterizing the public health, economic, health system, and individual burden caused by fungal diseases can provide critical insights to promote better prevention and treatment. The development and validation of fungal diagnostic tests that are rapid, accurate, and cost-effective can improve testing practices. Understanding best practices for antifungal prophylaxis can optimize prevention in at-risk populations, while research on antifungal resistance can improve patient outcomes. Investment in vaccines may eliminate certain fungal diseases or lower incidence and mortality. Public health research priorities and approaches may vary by fungal pathogen. MDPI 2023-08-03 /pmc/articles/PMC10455901/ /pubmed/37623591 http://dx.doi.org/10.3390/jof9080820 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Smith, Dallas J.
Gold, Jeremy A. W.
Benedict, Kaitlin
Wu, Karen
Lyman, Meghan
Jordan, Alexander
Medina, Narda
Lockhart, Shawn R.
Sexton, D. Joseph
Chow, Nancy A.
Jackson, Brendan R.
Litvintseva, Anastasia P.
Toda, Mitsuru
Chiller, Tom
Public Health Research Priorities for Fungal Diseases: A Multidisciplinary Approach to Save Lives
title Public Health Research Priorities for Fungal Diseases: A Multidisciplinary Approach to Save Lives
title_full Public Health Research Priorities for Fungal Diseases: A Multidisciplinary Approach to Save Lives
title_fullStr Public Health Research Priorities for Fungal Diseases: A Multidisciplinary Approach to Save Lives
title_full_unstemmed Public Health Research Priorities for Fungal Diseases: A Multidisciplinary Approach to Save Lives
title_short Public Health Research Priorities for Fungal Diseases: A Multidisciplinary Approach to Save Lives
title_sort public health research priorities for fungal diseases: a multidisciplinary approach to save lives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455901/
https://www.ncbi.nlm.nih.gov/pubmed/37623591
http://dx.doi.org/10.3390/jof9080820
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