Inhibitory Effects of Simvastatin on IL-33-Induced MCP-1 via the Suppression of the JNK Pathway in Human Vascular Endothelial Cells

An alarmin, interleukin (IL)-33 is a danger signal that causes inflammation, inducing chemotactic proteins such as monocyte chemoattractant protein (MCP)-1 in various cells. As statins have pleiotropic actions including anti-inflammatory properties, we investigated the effects of simvastatin on IL-3...

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Detalles Bibliográficos
Autores principales: Umebashi, Katsuyuki, Yamamoto, Masayoshi, Tokito, Akinori, Sudou, Ku, Takenoshita, Yoko, Jougasaki, Michihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456058/
https://www.ncbi.nlm.nih.gov/pubmed/37629196
http://dx.doi.org/10.3390/ijms241613015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456058/
https://www.ncbi.nlm.nih.gov/pubmed/37629196
http://dx.doi.org/10.3390/ijms241613015

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