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Inhibitory Effects of Simvastatin on IL-33-Induced MCP-1 via the Suppression of the JNK Pathway in Human Vascular Endothelial Cells
An alarmin, interleukin (IL)-33 is a danger signal that causes inflammation, inducing chemotactic proteins such as monocyte chemoattractant protein (MCP)-1 in various cells. As statins have pleiotropic actions including anti-inflammatory properties, we investigated the effects of simvastatin on IL-3...
Autores principales: | Umebashi, Katsuyuki, Yamamoto, Masayoshi, Tokito, Akinori, Sudou, Ku, Takenoshita, Yoko, Jougasaki, Michihisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456058/ https://www.ncbi.nlm.nih.gov/pubmed/37629196 http://dx.doi.org/10.3390/ijms241613015 |
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