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Burden of Disease; the Current Status of the Diagnosis and Management of Atopic Dermatitis in China

Atopic dermatitis (AD) is now a global health problem and has been attracting extensive attention from both academic and public society in China. This review aimed to present the current status of the prevalence, disease burden, clinical features, diagnosis, and management of AD in China. The preval...

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Detalles Bibliográficos
Autores principales: Gu, Chaoying, Yao, Xu, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456078/
https://www.ncbi.nlm.nih.gov/pubmed/37629411
http://dx.doi.org/10.3390/jcm12165370
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author Gu, Chaoying
Yao, Xu
Li, Wei
author_facet Gu, Chaoying
Yao, Xu
Li, Wei
author_sort Gu, Chaoying
collection PubMed
description Atopic dermatitis (AD) is now a global health problem and has been attracting extensive attention from both academic and public society in China. This review aimed to present the current status of the prevalence, disease burden, clinical features, diagnosis, and management of AD in China. The prevalence of AD has been increasing rapidly in China during the past decades, partially due to the increased recognition of the disease; there are still substantial amounts of over-diagnosed eczema and under-diagnosed AD. Chinese dermatologists see many AD patients with atypical manifestation, which poses a challenge to the diagnosis. The Chinese diagnostic criteria for adults and pediatric patients with AD have been proposed respectively and validated with high sensitivity and specificity. International and Chinese guidelines for management of AD have been popularized; however, there are still many practices that need verification through randomized case-control study. Dupilumab and JAK inhibitors have demonstrated favorable efficacy for AD patients in China, and a multidimensional approach is needed for selection of the patients and evaluation of the efficacy and safety. Patient education and long-term management for AD are just beginning in China, and need to be strengthened in the future.
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spelling pubmed-104560782023-08-26 Burden of Disease; the Current Status of the Diagnosis and Management of Atopic Dermatitis in China Gu, Chaoying Yao, Xu Li, Wei J Clin Med Review Atopic dermatitis (AD) is now a global health problem and has been attracting extensive attention from both academic and public society in China. This review aimed to present the current status of the prevalence, disease burden, clinical features, diagnosis, and management of AD in China. The prevalence of AD has been increasing rapidly in China during the past decades, partially due to the increased recognition of the disease; there are still substantial amounts of over-diagnosed eczema and under-diagnosed AD. Chinese dermatologists see many AD patients with atypical manifestation, which poses a challenge to the diagnosis. The Chinese diagnostic criteria for adults and pediatric patients with AD have been proposed respectively and validated with high sensitivity and specificity. International and Chinese guidelines for management of AD have been popularized; however, there are still many practices that need verification through randomized case-control study. Dupilumab and JAK inhibitors have demonstrated favorable efficacy for AD patients in China, and a multidimensional approach is needed for selection of the patients and evaluation of the efficacy and safety. Patient education and long-term management for AD are just beginning in China, and need to be strengthened in the future. MDPI 2023-08-18 /pmc/articles/PMC10456078/ /pubmed/37629411 http://dx.doi.org/10.3390/jcm12165370 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gu, Chaoying
Yao, Xu
Li, Wei
Burden of Disease; the Current Status of the Diagnosis and Management of Atopic Dermatitis in China
title Burden of Disease; the Current Status of the Diagnosis and Management of Atopic Dermatitis in China
title_full Burden of Disease; the Current Status of the Diagnosis and Management of Atopic Dermatitis in China
title_fullStr Burden of Disease; the Current Status of the Diagnosis and Management of Atopic Dermatitis in China
title_full_unstemmed Burden of Disease; the Current Status of the Diagnosis and Management of Atopic Dermatitis in China
title_short Burden of Disease; the Current Status of the Diagnosis and Management of Atopic Dermatitis in China
title_sort burden of disease; the current status of the diagnosis and management of atopic dermatitis in china
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456078/
https://www.ncbi.nlm.nih.gov/pubmed/37629411
http://dx.doi.org/10.3390/jcm12165370
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