Cargando…

Pain in High-Dose-Rate Brachytherapy for Cervical Cancer: A Retrospective Cohort Study

High-dose-rate brachytherapy (HDR) is part of the main treatment for locally advanced uterine cervical cancer. Our aim was to evaluate the incidence and intensity of pain and patients’ satisfaction during HDR. Risk factors for suffering pain were also analyzed. A retrospective study was carried out...

Descripción completa

Detalles Bibliográficos
Autores principales: Becerra-Bolaños, Ángel, Jiménez-Gil, Miriam, Federico, Mario, Domínguez-Díaz, Yurena, Valencia, Lucía, Rodríguez-Pérez, Aurelio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456084/
https://www.ncbi.nlm.nih.gov/pubmed/37623438
http://dx.doi.org/10.3390/jpm13081187
_version_ 1785096611041378304
author Becerra-Bolaños, Ángel
Jiménez-Gil, Miriam
Federico, Mario
Domínguez-Díaz, Yurena
Valencia, Lucía
Rodríguez-Pérez, Aurelio
author_facet Becerra-Bolaños, Ángel
Jiménez-Gil, Miriam
Federico, Mario
Domínguez-Díaz, Yurena
Valencia, Lucía
Rodríguez-Pérez, Aurelio
author_sort Becerra-Bolaños, Ángel
collection PubMed
description High-dose-rate brachytherapy (HDR) is part of the main treatment for locally advanced uterine cervical cancer. Our aim was to evaluate the incidence and intensity of pain and patients’ satisfaction during HDR. Risk factors for suffering pain were also analyzed. A retrospective study was carried out by extracting data from patients who had received HDR treatment for five years. Postoperative analgesia had been administered using pre-established analgesic protocols for 48 h. Pain assessment was collected according to a protocol by the acute pain unit. Analgesic assessment was compared according to analgesic protocol administered, number of needles implanted, and type of anesthesia performed during the procedure. From 172 patients treated, data from 247 treatments were analyzed. Pain was considered moderate in 18.2% of the patients, and 43.3% of the patients required at least one analgesic rescue. Patients receiving major opioids reported worse pain control. No differences were found regarding the analgesic management according to the intraprocedural anesthesia used or the patients’ characteristics. The number of inserted needles did not influence the postoperative analgesic assessment. Continuous intravenous infusion of tramadol and metamizole made peri-procedural pain during HDR mild in most cases. Many patients still suffered from moderate pain.
format Online
Article
Text
id pubmed-10456084
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-104560842023-08-26 Pain in High-Dose-Rate Brachytherapy for Cervical Cancer: A Retrospective Cohort Study Becerra-Bolaños, Ángel Jiménez-Gil, Miriam Federico, Mario Domínguez-Díaz, Yurena Valencia, Lucía Rodríguez-Pérez, Aurelio J Pers Med Article High-dose-rate brachytherapy (HDR) is part of the main treatment for locally advanced uterine cervical cancer. Our aim was to evaluate the incidence and intensity of pain and patients’ satisfaction during HDR. Risk factors for suffering pain were also analyzed. A retrospective study was carried out by extracting data from patients who had received HDR treatment for five years. Postoperative analgesia had been administered using pre-established analgesic protocols for 48 h. Pain assessment was collected according to a protocol by the acute pain unit. Analgesic assessment was compared according to analgesic protocol administered, number of needles implanted, and type of anesthesia performed during the procedure. From 172 patients treated, data from 247 treatments were analyzed. Pain was considered moderate in 18.2% of the patients, and 43.3% of the patients required at least one analgesic rescue. Patients receiving major opioids reported worse pain control. No differences were found regarding the analgesic management according to the intraprocedural anesthesia used or the patients’ characteristics. The number of inserted needles did not influence the postoperative analgesic assessment. Continuous intravenous infusion of tramadol and metamizole made peri-procedural pain during HDR mild in most cases. Many patients still suffered from moderate pain. MDPI 2023-07-26 /pmc/articles/PMC10456084/ /pubmed/37623438 http://dx.doi.org/10.3390/jpm13081187 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Becerra-Bolaños, Ángel
Jiménez-Gil, Miriam
Federico, Mario
Domínguez-Díaz, Yurena
Valencia, Lucía
Rodríguez-Pérez, Aurelio
Pain in High-Dose-Rate Brachytherapy for Cervical Cancer: A Retrospective Cohort Study
title Pain in High-Dose-Rate Brachytherapy for Cervical Cancer: A Retrospective Cohort Study
title_full Pain in High-Dose-Rate Brachytherapy for Cervical Cancer: A Retrospective Cohort Study
title_fullStr Pain in High-Dose-Rate Brachytherapy for Cervical Cancer: A Retrospective Cohort Study
title_full_unstemmed Pain in High-Dose-Rate Brachytherapy for Cervical Cancer: A Retrospective Cohort Study
title_short Pain in High-Dose-Rate Brachytherapy for Cervical Cancer: A Retrospective Cohort Study
title_sort pain in high-dose-rate brachytherapy for cervical cancer: a retrospective cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456084/
https://www.ncbi.nlm.nih.gov/pubmed/37623438
http://dx.doi.org/10.3390/jpm13081187
work_keys_str_mv AT becerrabolanosangel paininhighdoseratebrachytherapyforcervicalcanceraretrospectivecohortstudy
AT jimenezgilmiriam paininhighdoseratebrachytherapyforcervicalcanceraretrospectivecohortstudy
AT federicomario paininhighdoseratebrachytherapyforcervicalcanceraretrospectivecohortstudy
AT dominguezdiazyurena paininhighdoseratebrachytherapyforcervicalcanceraretrospectivecohortstudy
AT valencialucia paininhighdoseratebrachytherapyforcervicalcanceraretrospectivecohortstudy
AT rodriguezperezaurelio paininhighdoseratebrachytherapyforcervicalcanceraretrospectivecohortstudy