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Breakdown of Phospholipid Asymmetry Triggers ADAM17-Mediated Rescue Events in Cells Undergoing Apoptosis

ADAM17, a prominent member of the “Disintegrin and Metalloproteinase” (ADAM) family, controls vital cellular functions through the cleavage of transmembrane substrates, including epidermal growth factor receptor (EGFR) ligands such as transforming growth factor (TGF)-alpha and Epiregulin (EREG). Sev...

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Detalles Bibliográficos
Autores principales: Sperrhacke, Maria, Leitzke, Sinje, Ahrens, Björn, Reiss, Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456294/
https://www.ncbi.nlm.nih.gov/pubmed/37623781
http://dx.doi.org/10.3390/membranes13080720