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Metformin Can Attenuate Beta-Cell Hypersecretion—Implications for Treatment of Children with Obesity
In children with obesity, insulin hypersecretion is proposed to precede insulin resistance. We investigated if metformin could be used to attenuate insulin secretion from palmitate-treated isolated islets and its implication for children with obesity. Human islets were exposed to palmitate for 0.5 o...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456302/ https://www.ncbi.nlm.nih.gov/pubmed/37623862 http://dx.doi.org/10.3390/metabo13080917 |