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Preliminary Study of Axillary Lymphatic Drainage in Cutaneous Melanoma Patients: A Cross-Sectional Study

Background: The axilla is a region of fundamental importance for the implications during oncological surgery, and there are many classifications of axillary lymph node subdivision: on the basis of studies on women with breast cancer, we used Clough’s and Li’s classification. However, currently we do...

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Autores principales: Cirocchi, Roberto, Cicoletti, Michela, Arcangeli, Fabrizio, Tebala, Giovanni D., Bruzzone, Paolo, Avenia, Stefano, Poli, Giulia, Trastulli, Stefano, Matteucci, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456326/
https://www.ncbi.nlm.nih.gov/pubmed/37629647
http://dx.doi.org/10.3390/medicina59081357
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author Cirocchi, Roberto
Cicoletti, Michela
Arcangeli, Fabrizio
Tebala, Giovanni D.
Bruzzone, Paolo
Avenia, Stefano
Poli, Giulia
Trastulli, Stefano
Matteucci, Matteo
author_facet Cirocchi, Roberto
Cicoletti, Michela
Arcangeli, Fabrizio
Tebala, Giovanni D.
Bruzzone, Paolo
Avenia, Stefano
Poli, Giulia
Trastulli, Stefano
Matteucci, Matteo
author_sort Cirocchi, Roberto
collection PubMed
description Background: The axilla is a region of fundamental importance for the implications during oncological surgery, and there are many classifications of axillary lymph node subdivision: on the basis of studies on women with breast cancer, we used Clough’s and Li’s classification. However, currently we do not have a gold-standard classification regarding axillary lymphatic drainage in melanoma patients. Purpose: Our aim was to evaluate how these classifications could be adapted to sentinel lymph node evaluation in skin-melanoma patients and to look for a possible correlation between the most recent classifications of axillary lymph node location and Oeslner’s classification, one of the most common anatomical classifications still widespread today. Methods: We analyzed data from 21 patients who underwent sentinel lymph node biopsy between January 2021 and January 2022. Results: Our study demonstrates that, to an extent, there is a possible difference in the use of the various classifications, hinting at possible limits of each. The data we obtained underline how cutaneous melanoma presents extremely heterogenous lymphatic drainage at the level of the axillary cavity. However, the limited data in our possession do not allow us to obtain, at the moment, results that are statistically significant, although we are continuing to enroll patients and collect data. Conclusions: Results of this study support the evidence that the common classifications used for breast cancer do not seem to be exhaustive. Therefore, a specific axillary lymph node classification is necessary in skin melanoma patients.
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spelling pubmed-104563262023-08-26 Preliminary Study of Axillary Lymphatic Drainage in Cutaneous Melanoma Patients: A Cross-Sectional Study Cirocchi, Roberto Cicoletti, Michela Arcangeli, Fabrizio Tebala, Giovanni D. Bruzzone, Paolo Avenia, Stefano Poli, Giulia Trastulli, Stefano Matteucci, Matteo Medicina (Kaunas) Article Background: The axilla is a region of fundamental importance for the implications during oncological surgery, and there are many classifications of axillary lymph node subdivision: on the basis of studies on women with breast cancer, we used Clough’s and Li’s classification. However, currently we do not have a gold-standard classification regarding axillary lymphatic drainage in melanoma patients. Purpose: Our aim was to evaluate how these classifications could be adapted to sentinel lymph node evaluation in skin-melanoma patients and to look for a possible correlation between the most recent classifications of axillary lymph node location and Oeslner’s classification, one of the most common anatomical classifications still widespread today. Methods: We analyzed data from 21 patients who underwent sentinel lymph node biopsy between January 2021 and January 2022. Results: Our study demonstrates that, to an extent, there is a possible difference in the use of the various classifications, hinting at possible limits of each. The data we obtained underline how cutaneous melanoma presents extremely heterogenous lymphatic drainage at the level of the axillary cavity. However, the limited data in our possession do not allow us to obtain, at the moment, results that are statistically significant, although we are continuing to enroll patients and collect data. Conclusions: Results of this study support the evidence that the common classifications used for breast cancer do not seem to be exhaustive. Therefore, a specific axillary lymph node classification is necessary in skin melanoma patients. MDPI 2023-07-25 /pmc/articles/PMC10456326/ /pubmed/37629647 http://dx.doi.org/10.3390/medicina59081357 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cirocchi, Roberto
Cicoletti, Michela
Arcangeli, Fabrizio
Tebala, Giovanni D.
Bruzzone, Paolo
Avenia, Stefano
Poli, Giulia
Trastulli, Stefano
Matteucci, Matteo
Preliminary Study of Axillary Lymphatic Drainage in Cutaneous Melanoma Patients: A Cross-Sectional Study
title Preliminary Study of Axillary Lymphatic Drainage in Cutaneous Melanoma Patients: A Cross-Sectional Study
title_full Preliminary Study of Axillary Lymphatic Drainage in Cutaneous Melanoma Patients: A Cross-Sectional Study
title_fullStr Preliminary Study of Axillary Lymphatic Drainage in Cutaneous Melanoma Patients: A Cross-Sectional Study
title_full_unstemmed Preliminary Study of Axillary Lymphatic Drainage in Cutaneous Melanoma Patients: A Cross-Sectional Study
title_short Preliminary Study of Axillary Lymphatic Drainage in Cutaneous Melanoma Patients: A Cross-Sectional Study
title_sort preliminary study of axillary lymphatic drainage in cutaneous melanoma patients: a cross-sectional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456326/
https://www.ncbi.nlm.nih.gov/pubmed/37629647
http://dx.doi.org/10.3390/medicina59081357
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