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Gallbladder Pancreatic Heterotopia—The Importance of Diagnostic Imaging in Managing Intraoperative Findings

Pancreatic heterotopy is a rare entity defined as the presence of abnormally located pancreatic tissue without any anatomical or vascular connection to the normal pancreas. Heterotopic pancreatic tissue can be found in various regions of the digestive system, such as the stomach, duodenum, and upper...

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Autores principales: Şerboiu, Crenguţa Sorina, Aliuș, Cătălin, Dumitru, Adrian, Țăpoi, Dana, Costache, Mariana, Nica, Adriana Elena, Alexandra-Ana, Mihăilescu, Antoniac, Iulian, Grădinaru, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456474/
https://www.ncbi.nlm.nih.gov/pubmed/37629697
http://dx.doi.org/10.3390/medicina59081407
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author Şerboiu, Crenguţa Sorina
Aliuș, Cătălin
Dumitru, Adrian
Țăpoi, Dana
Costache, Mariana
Nica, Adriana Elena
Alexandra-Ana, Mihăilescu
Antoniac, Iulian
Grădinaru, Sebastian
author_facet Şerboiu, Crenguţa Sorina
Aliuș, Cătălin
Dumitru, Adrian
Țăpoi, Dana
Costache, Mariana
Nica, Adriana Elena
Alexandra-Ana, Mihăilescu
Antoniac, Iulian
Grădinaru, Sebastian
author_sort Şerboiu, Crenguţa Sorina
collection PubMed
description Pancreatic heterotopy is a rare entity defined as the presence of abnormally located pancreatic tissue without any anatomical or vascular connection to the normal pancreas. Heterotopic pancreatic tissue can be found in various regions of the digestive system, such as the stomach, duodenum, and upper jejunum, with the less commonly reported location being the gallbladder. Gallbladder pancreatic heterotopia can be either an incidental finding or diagnosed in association with cholecystitis. Pancreatitis of the ectopic tissue has also been described. In this context, we report three cases of heterotopic pancreatic tissue in the gallbladder with different types of pancreatic tissue according to the Heinrich classification. One patient was a 24-year-old male who presented with acute pancreatitis symptoms and an ultrasonographical detected mass in the gallbladder, which proved to be heterotopic pancreatic tissue. The other two cases were female patients aged 24 and 32, respectively, incidentally diagnosed on histopathological examination after cholecystectomy for symptomatic cholelithiasis. Both cases displayed chronic cholecystitis lesions; one of them was also associated with low grade dysplasia of the gallbladder. Although a rare occurrence in general, pancreatic heterotopia should be acknowledged as a possible incidental finding in asymptomatic patients as well as a cause for acute cholecystitis or pancreatitis.
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spelling pubmed-104564742023-08-26 Gallbladder Pancreatic Heterotopia—The Importance of Diagnostic Imaging in Managing Intraoperative Findings Şerboiu, Crenguţa Sorina Aliuș, Cătălin Dumitru, Adrian Țăpoi, Dana Costache, Mariana Nica, Adriana Elena Alexandra-Ana, Mihăilescu Antoniac, Iulian Grădinaru, Sebastian Medicina (Kaunas) Review Pancreatic heterotopy is a rare entity defined as the presence of abnormally located pancreatic tissue without any anatomical or vascular connection to the normal pancreas. Heterotopic pancreatic tissue can be found in various regions of the digestive system, such as the stomach, duodenum, and upper jejunum, with the less commonly reported location being the gallbladder. Gallbladder pancreatic heterotopia can be either an incidental finding or diagnosed in association with cholecystitis. Pancreatitis of the ectopic tissue has also been described. In this context, we report three cases of heterotopic pancreatic tissue in the gallbladder with different types of pancreatic tissue according to the Heinrich classification. One patient was a 24-year-old male who presented with acute pancreatitis symptoms and an ultrasonographical detected mass in the gallbladder, which proved to be heterotopic pancreatic tissue. The other two cases were female patients aged 24 and 32, respectively, incidentally diagnosed on histopathological examination after cholecystectomy for symptomatic cholelithiasis. Both cases displayed chronic cholecystitis lesions; one of them was also associated with low grade dysplasia of the gallbladder. Although a rare occurrence in general, pancreatic heterotopia should be acknowledged as a possible incidental finding in asymptomatic patients as well as a cause for acute cholecystitis or pancreatitis. MDPI 2023-08-01 /pmc/articles/PMC10456474/ /pubmed/37629697 http://dx.doi.org/10.3390/medicina59081407 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Şerboiu, Crenguţa Sorina
Aliuș, Cătălin
Dumitru, Adrian
Țăpoi, Dana
Costache, Mariana
Nica, Adriana Elena
Alexandra-Ana, Mihăilescu
Antoniac, Iulian
Grădinaru, Sebastian
Gallbladder Pancreatic Heterotopia—The Importance of Diagnostic Imaging in Managing Intraoperative Findings
title Gallbladder Pancreatic Heterotopia—The Importance of Diagnostic Imaging in Managing Intraoperative Findings
title_full Gallbladder Pancreatic Heterotopia—The Importance of Diagnostic Imaging in Managing Intraoperative Findings
title_fullStr Gallbladder Pancreatic Heterotopia—The Importance of Diagnostic Imaging in Managing Intraoperative Findings
title_full_unstemmed Gallbladder Pancreatic Heterotopia—The Importance of Diagnostic Imaging in Managing Intraoperative Findings
title_short Gallbladder Pancreatic Heterotopia—The Importance of Diagnostic Imaging in Managing Intraoperative Findings
title_sort gallbladder pancreatic heterotopia—the importance of diagnostic imaging in managing intraoperative findings
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456474/
https://www.ncbi.nlm.nih.gov/pubmed/37629697
http://dx.doi.org/10.3390/medicina59081407
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