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The Cardiac Comeback-Beating Stronger: Exploring the Remarkable Resilience of the Heart in COVID-19 Recovery through Cardiac Autonomic Analysis

Background and Objectives: Analyzing the cardiac autonomic function in COVID-19 patients can provide insights into the impact of the virus on the heart’s regulatory mechanisms and its recovery. The autonomic nervous system plays a crucial role in regulating the heart’s functions, such as heart rate,...

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Autores principales: Garg, Sakshi, Saini, Preeti, Rizvi, Moattar Raza, Ahmad, Fuzail, AlTaweel, Mohammed, Sabah, Zia Ul, Durrani, Humayoun K., Almasswary, Shatha A., Seyam, Mohamed K., Sharma, Ankita, Ahmad, Irshad, Marzoogi, Sara Al, Shaphe, Mohammad A., Uddin, Shadab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456477/
https://www.ncbi.nlm.nih.gov/pubmed/37629687
http://dx.doi.org/10.3390/medicina59081397
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author Garg, Sakshi
Saini, Preeti
Rizvi, Moattar Raza
Ahmad, Fuzail
AlTaweel, Mohammed
Sabah, Zia Ul
Durrani, Humayoun K.
Almasswary, Shatha A.
Seyam, Mohamed K.
Sharma, Ankita
Ahmad, Irshad
Marzoogi, Sara Al
Shaphe, Mohammad A.
Uddin, Shadab
Ahmad, Irshad
author_facet Garg, Sakshi
Saini, Preeti
Rizvi, Moattar Raza
Ahmad, Fuzail
AlTaweel, Mohammed
Sabah, Zia Ul
Durrani, Humayoun K.
Almasswary, Shatha A.
Seyam, Mohamed K.
Sharma, Ankita
Ahmad, Irshad
Marzoogi, Sara Al
Shaphe, Mohammad A.
Uddin, Shadab
Ahmad, Irshad
author_sort Garg, Sakshi
collection PubMed
description Background and Objectives: Analyzing the cardiac autonomic function in COVID-19 patients can provide insights into the impact of the virus on the heart’s regulatory mechanisms and its recovery. The autonomic nervous system plays a crucial role in regulating the heart’s functions, such as heart rate, blood pressure, and cardiac output. This study aimed to investigate the impact of COVID-19 on heart rate variability (HRV) during a 6-min walk test (6MWT). Materials and Methods: The study included 74 participants, consisting of 37 individuals who had recovered from mild to moderate COVID-19 and 37 healthy controls. The study assessed heart rate variability (HRV) and blood pressure both before and after a 6-min walk test (6MWT). Results: The study found significant differences in a few time domains (SDNN and pNN50) and all frequency domain measures, whereas there were no significant differences in demographic characteristics or blood pressure between COVID-19-recovered individuals and healthy controls at rest. There were significant 6MWT effects on average HR, time-domain (SDNN and pNN50) measures of HRV, and all frequency domain measures of HRV. A significant group × 6MWT interaction was found for SDNN, pNN50, total power, Ln total power, LF, HF, Ln LF, Ln HF, and LF nu. Conclusions: Cardiac Autonomic analysis through HRV is essential to ensure the continued health and well-being of COVID-19 survivors and to minimize the potential long-term impacts of the disease on their cardiovascular system. This suggests that HRV analysis during the recovery phase following exercise could serve as a valuable tool for evaluating the physiological effects of COVID-19 and monitoring the recovery process.
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spelling pubmed-104564772023-08-26 The Cardiac Comeback-Beating Stronger: Exploring the Remarkable Resilience of the Heart in COVID-19 Recovery through Cardiac Autonomic Analysis Garg, Sakshi Saini, Preeti Rizvi, Moattar Raza Ahmad, Fuzail AlTaweel, Mohammed Sabah, Zia Ul Durrani, Humayoun K. Almasswary, Shatha A. Seyam, Mohamed K. Sharma, Ankita Ahmad, Irshad Marzoogi, Sara Al Shaphe, Mohammad A. Uddin, Shadab Ahmad, Irshad Medicina (Kaunas) Article Background and Objectives: Analyzing the cardiac autonomic function in COVID-19 patients can provide insights into the impact of the virus on the heart’s regulatory mechanisms and its recovery. The autonomic nervous system plays a crucial role in regulating the heart’s functions, such as heart rate, blood pressure, and cardiac output. This study aimed to investigate the impact of COVID-19 on heart rate variability (HRV) during a 6-min walk test (6MWT). Materials and Methods: The study included 74 participants, consisting of 37 individuals who had recovered from mild to moderate COVID-19 and 37 healthy controls. The study assessed heart rate variability (HRV) and blood pressure both before and after a 6-min walk test (6MWT). Results: The study found significant differences in a few time domains (SDNN and pNN50) and all frequency domain measures, whereas there were no significant differences in demographic characteristics or blood pressure between COVID-19-recovered individuals and healthy controls at rest. There were significant 6MWT effects on average HR, time-domain (SDNN and pNN50) measures of HRV, and all frequency domain measures of HRV. A significant group × 6MWT interaction was found for SDNN, pNN50, total power, Ln total power, LF, HF, Ln LF, Ln HF, and LF nu. Conclusions: Cardiac Autonomic analysis through HRV is essential to ensure the continued health and well-being of COVID-19 survivors and to minimize the potential long-term impacts of the disease on their cardiovascular system. This suggests that HRV analysis during the recovery phase following exercise could serve as a valuable tool for evaluating the physiological effects of COVID-19 and monitoring the recovery process. MDPI 2023-07-30 /pmc/articles/PMC10456477/ /pubmed/37629687 http://dx.doi.org/10.3390/medicina59081397 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Garg, Sakshi
Saini, Preeti
Rizvi, Moattar Raza
Ahmad, Fuzail
AlTaweel, Mohammed
Sabah, Zia Ul
Durrani, Humayoun K.
Almasswary, Shatha A.
Seyam, Mohamed K.
Sharma, Ankita
Ahmad, Irshad
Marzoogi, Sara Al
Shaphe, Mohammad A.
Uddin, Shadab
Ahmad, Irshad
The Cardiac Comeback-Beating Stronger: Exploring the Remarkable Resilience of the Heart in COVID-19 Recovery through Cardiac Autonomic Analysis
title The Cardiac Comeback-Beating Stronger: Exploring the Remarkable Resilience of the Heart in COVID-19 Recovery through Cardiac Autonomic Analysis
title_full The Cardiac Comeback-Beating Stronger: Exploring the Remarkable Resilience of the Heart in COVID-19 Recovery through Cardiac Autonomic Analysis
title_fullStr The Cardiac Comeback-Beating Stronger: Exploring the Remarkable Resilience of the Heart in COVID-19 Recovery through Cardiac Autonomic Analysis
title_full_unstemmed The Cardiac Comeback-Beating Stronger: Exploring the Remarkable Resilience of the Heart in COVID-19 Recovery through Cardiac Autonomic Analysis
title_short The Cardiac Comeback-Beating Stronger: Exploring the Remarkable Resilience of the Heart in COVID-19 Recovery through Cardiac Autonomic Analysis
title_sort cardiac comeback-beating stronger: exploring the remarkable resilience of the heart in covid-19 recovery through cardiac autonomic analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456477/
https://www.ncbi.nlm.nih.gov/pubmed/37629687
http://dx.doi.org/10.3390/medicina59081397
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