Amyloid Precursor Protein Changes Arrangement in a Membrane and Its Structure Depending on the Cholesterol Content

One of the hallmarks of Alzheimer’s disease (AD) is the accumulation of amyloid beta (Aβ) peptides in the brain. The processing of amyloid precursor protein (APP) into Aβ is dependent on the location of APP in the membrane, membrane lipid composition and, possibly, presence of lipid rafts. In this s...

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Detalles Bibliográficos
Autores principales: Krasnobaev, Vladimir D., Bershatsky, Yaroslav V., Bocharova, Olga V., Bocharov, Eduard V., Batishchev, Oleg V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456541/
https://www.ncbi.nlm.nih.gov/pubmed/37623767
http://dx.doi.org/10.3390/membranes13080706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456541/
https://www.ncbi.nlm.nih.gov/pubmed/37623767
http://dx.doi.org/10.3390/membranes13080706

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