Cargando…

Identification of Secondary Metabolites from the Mangrove-Endophyte Lasiodiplodia iranensis F0619 by UPLC-ESI-MS/MS

Lasiodiplodia is a widely distributed fungal genus, frequently found in tropical and subtropical regions where it can cause disease in important crops. It represents a promising source of active secondary metabolites with uses in chemical, pharmaceutical, and agrochemical processes. In this study, t...

Descripción completa

Detalles Bibliográficos
Autores principales: Delgado Gómez, Lizbeth M., Torres-Mendoza, Daniel, Hernández-Torres, Kathleen, Ortega, Humberto E., Cubilla-Rios, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456654/
https://www.ncbi.nlm.nih.gov/pubmed/37623856
http://dx.doi.org/10.3390/metabo13080912
_version_ 1785096751427878912
author Delgado Gómez, Lizbeth M.
Torres-Mendoza, Daniel
Hernández-Torres, Kathleen
Ortega, Humberto E.
Cubilla-Rios, Luis
author_facet Delgado Gómez, Lizbeth M.
Torres-Mendoza, Daniel
Hernández-Torres, Kathleen
Ortega, Humberto E.
Cubilla-Rios, Luis
author_sort Delgado Gómez, Lizbeth M.
collection PubMed
description Lasiodiplodia is a widely distributed fungal genus, frequently found in tropical and subtropical regions where it can cause disease in important crops. It represents a promising source of active secondary metabolites with uses in chemical, pharmaceutical, and agrochemical processes. In this study, the strain Lasiodiplodia iranensis F0619 was isolated from the mangrove Avicennia ger-minans, collected from Sarigua National Park in the Republic of Panama. Fractions of crude extract were analyzed by UPLC-ESI-MS/MS, and five compounds, previously reported from Lasiodiplodia genus were identified, including 11,12-didehydro-7-iso-jasmonic acid (1), 4,5-didehydro-7-iso-jasmonic acid (2), cyclo-(L-Leu-L-Pro) (3), jasmonate-threonine (4), and abscisic acid (5). We describe and analyze their MS/MS fragmentation patterns to confirm the compounds ‘chemical structures.
format Online
Article
Text
id pubmed-10456654
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-104566542023-08-26 Identification of Secondary Metabolites from the Mangrove-Endophyte Lasiodiplodia iranensis F0619 by UPLC-ESI-MS/MS Delgado Gómez, Lizbeth M. Torres-Mendoza, Daniel Hernández-Torres, Kathleen Ortega, Humberto E. Cubilla-Rios, Luis Metabolites Article Lasiodiplodia is a widely distributed fungal genus, frequently found in tropical and subtropical regions where it can cause disease in important crops. It represents a promising source of active secondary metabolites with uses in chemical, pharmaceutical, and agrochemical processes. In this study, the strain Lasiodiplodia iranensis F0619 was isolated from the mangrove Avicennia ger-minans, collected from Sarigua National Park in the Republic of Panama. Fractions of crude extract were analyzed by UPLC-ESI-MS/MS, and five compounds, previously reported from Lasiodiplodia genus were identified, including 11,12-didehydro-7-iso-jasmonic acid (1), 4,5-didehydro-7-iso-jasmonic acid (2), cyclo-(L-Leu-L-Pro) (3), jasmonate-threonine (4), and abscisic acid (5). We describe and analyze their MS/MS fragmentation patterns to confirm the compounds ‘chemical structures. MDPI 2023-08-03 /pmc/articles/PMC10456654/ /pubmed/37623856 http://dx.doi.org/10.3390/metabo13080912 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Delgado Gómez, Lizbeth M.
Torres-Mendoza, Daniel
Hernández-Torres, Kathleen
Ortega, Humberto E.
Cubilla-Rios, Luis
Identification of Secondary Metabolites from the Mangrove-Endophyte Lasiodiplodia iranensis F0619 by UPLC-ESI-MS/MS
title Identification of Secondary Metabolites from the Mangrove-Endophyte Lasiodiplodia iranensis F0619 by UPLC-ESI-MS/MS
title_full Identification of Secondary Metabolites from the Mangrove-Endophyte Lasiodiplodia iranensis F0619 by UPLC-ESI-MS/MS
title_fullStr Identification of Secondary Metabolites from the Mangrove-Endophyte Lasiodiplodia iranensis F0619 by UPLC-ESI-MS/MS
title_full_unstemmed Identification of Secondary Metabolites from the Mangrove-Endophyte Lasiodiplodia iranensis F0619 by UPLC-ESI-MS/MS
title_short Identification of Secondary Metabolites from the Mangrove-Endophyte Lasiodiplodia iranensis F0619 by UPLC-ESI-MS/MS
title_sort identification of secondary metabolites from the mangrove-endophyte lasiodiplodia iranensis f0619 by uplc-esi-ms/ms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456654/
https://www.ncbi.nlm.nih.gov/pubmed/37623856
http://dx.doi.org/10.3390/metabo13080912
work_keys_str_mv AT delgadogomezlizbethm identificationofsecondarymetabolitesfromthemangroveendophytelasiodiplodiairanensisf0619byuplcesimsms
AT torresmendozadaniel identificationofsecondarymetabolitesfromthemangroveendophytelasiodiplodiairanensisf0619byuplcesimsms
AT hernandeztorreskathleen identificationofsecondarymetabolitesfromthemangroveendophytelasiodiplodiairanensisf0619byuplcesimsms
AT ortegahumbertoe identificationofsecondarymetabolitesfromthemangroveendophytelasiodiplodiairanensisf0619byuplcesimsms
AT cubillariosluis identificationofsecondarymetabolitesfromthemangroveendophytelasiodiplodiairanensisf0619byuplcesimsms