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Autoimmune Heart Disease: A Comprehensive Summary for Forensic Practice
Autoimmune heart disease is a non-random condition characterised by immune system-mediated aggression against cardiac tissue. Cardiac changes often exhibit nonspecific features and, if unrecognised, can result in fatal outcomes even among seemingly healthy young individuals. In the absence of reliab...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456745/ https://www.ncbi.nlm.nih.gov/pubmed/37629654 http://dx.doi.org/10.3390/medicina59081364 |
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author | Mezzetti, Eleonora Costantino, Andrea Leoni, Matteo Pieretti, Rebecca Di Paolo, Marco Frati, Paola Maiese, Aniello Fineschi, Vittorio |
author_facet | Mezzetti, Eleonora Costantino, Andrea Leoni, Matteo Pieretti, Rebecca Di Paolo, Marco Frati, Paola Maiese, Aniello Fineschi, Vittorio |
author_sort | Mezzetti, Eleonora |
collection | PubMed |
description | Autoimmune heart disease is a non-random condition characterised by immune system-mediated aggression against cardiac tissue. Cardiac changes often exhibit nonspecific features and, if unrecognised, can result in fatal outcomes even among seemingly healthy young individuals. In the absence of reliable medical history, the primary challenge lies in differentiating between the various cardiopathies. Numerous immunohistochemical and genetic studies have endeavoured to characterise distinct types of cardiopathies, facilitating their differentiation during autopsy examinations. However, the presence of a standardised protocol that forensic pathologists can employ to guide their investigations would be beneficial. Hence, this summary aims to present the spectrum of autoimmune cardiopathies, including emerging insights such as SARS-CoV-2-induced cardiopathies, and proposes the utilisation of practical tools, such as blood markers, to aid forensic pathologists in their routine practice. |
format | Online Article Text |
id | pubmed-10456745 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104567452023-08-26 Autoimmune Heart Disease: A Comprehensive Summary for Forensic Practice Mezzetti, Eleonora Costantino, Andrea Leoni, Matteo Pieretti, Rebecca Di Paolo, Marco Frati, Paola Maiese, Aniello Fineschi, Vittorio Medicina (Kaunas) Review Autoimmune heart disease is a non-random condition characterised by immune system-mediated aggression against cardiac tissue. Cardiac changes often exhibit nonspecific features and, if unrecognised, can result in fatal outcomes even among seemingly healthy young individuals. In the absence of reliable medical history, the primary challenge lies in differentiating between the various cardiopathies. Numerous immunohistochemical and genetic studies have endeavoured to characterise distinct types of cardiopathies, facilitating their differentiation during autopsy examinations. However, the presence of a standardised protocol that forensic pathologists can employ to guide their investigations would be beneficial. Hence, this summary aims to present the spectrum of autoimmune cardiopathies, including emerging insights such as SARS-CoV-2-induced cardiopathies, and proposes the utilisation of practical tools, such as blood markers, to aid forensic pathologists in their routine practice. MDPI 2023-07-25 /pmc/articles/PMC10456745/ /pubmed/37629654 http://dx.doi.org/10.3390/medicina59081364 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Mezzetti, Eleonora Costantino, Andrea Leoni, Matteo Pieretti, Rebecca Di Paolo, Marco Frati, Paola Maiese, Aniello Fineschi, Vittorio Autoimmune Heart Disease: A Comprehensive Summary for Forensic Practice |
title | Autoimmune Heart Disease: A Comprehensive Summary for Forensic Practice |
title_full | Autoimmune Heart Disease: A Comprehensive Summary for Forensic Practice |
title_fullStr | Autoimmune Heart Disease: A Comprehensive Summary for Forensic Practice |
title_full_unstemmed | Autoimmune Heart Disease: A Comprehensive Summary for Forensic Practice |
title_short | Autoimmune Heart Disease: A Comprehensive Summary for Forensic Practice |
title_sort | autoimmune heart disease: a comprehensive summary for forensic practice |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456745/ https://www.ncbi.nlm.nih.gov/pubmed/37629654 http://dx.doi.org/10.3390/medicina59081364 |
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