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Evaluation of Blood Pressure Status and Mortality in Turkey: Findings from Chronic Diseases and Risk Factors Cohort Study

Background and objectives: An important Non-Communicable Disease risk factor, hypertension (HT), is highly prevalent and controlled HT rates are not sufficient which increases the risk of developing premature deaths. The purpose of the study is to evaluate differences in all-cause and cardiovascular...

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Autores principales: Sozmen, Kaan, Ergor, Gul, Sakarya, Sibel, Dinc Horasan, Gonul, Sahan, Ceyda, Ekinci, Banu, Arikan, Ahmet, Sis, Secil, Unal, Belgin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456768/
https://www.ncbi.nlm.nih.gov/pubmed/37629656
http://dx.doi.org/10.3390/medicina59081366
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author Sozmen, Kaan
Ergor, Gul
Sakarya, Sibel
Dinc Horasan, Gonul
Sahan, Ceyda
Ekinci, Banu
Arikan, Ahmet
Sis, Secil
Unal, Belgin
author_facet Sozmen, Kaan
Ergor, Gul
Sakarya, Sibel
Dinc Horasan, Gonul
Sahan, Ceyda
Ekinci, Banu
Arikan, Ahmet
Sis, Secil
Unal, Belgin
author_sort Sozmen, Kaan
collection PubMed
description Background and objectives: An important Non-Communicable Disease risk factor, hypertension (HT), is highly prevalent and controlled HT rates are not sufficient which increases the risk of developing premature deaths. The purpose of the study is to evaluate differences in all-cause and cardiovascular-related mortality according to HT status by using national data from Chronic Diseases and Risk Factors Survey in Turkey (2011–2017). Materials and Methods: Cox regression models were used to estimate hazard ratios (HR) for predicting the all-cause and cardiovascular system-related mortalities. Median follow-up period was 6.2 years. Results: Among individuals with HT, 41.8% was untreated, 30.1% received treatment and had controlled blood pressure, and 28.1% were under treatment but had uncontrolled BP levels. The hazard for mortality among treated & uncontrolled hypertensive participants was significantly higher for all-cause (HR = 1.32, 95% CI = 1.06–1.65), cardiovascular (HR = 2.11, 95% CI = 1.46–3.06), heart disease (HR = 2.24, 95% CI = 1.46–3.43), and Coronary Heart Disease mortality (HR = 2.66, 95% CI = 1.56–4.53) compared to normotensive participants. Conclusions: Individuals with HT who were treated but do not have controlled blood pressure in Turkey had a significantly increased risk of Cardiovascular Disease and all-cause mortality. Along with studies investigating the causes of uncontrolled blood pressure despite initiation of treatment, support should be provided to patients in cases of non-adherence to antihypertensive medication or life change recommendations.
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spelling pubmed-104567682023-08-26 Evaluation of Blood Pressure Status and Mortality in Turkey: Findings from Chronic Diseases and Risk Factors Cohort Study Sozmen, Kaan Ergor, Gul Sakarya, Sibel Dinc Horasan, Gonul Sahan, Ceyda Ekinci, Banu Arikan, Ahmet Sis, Secil Unal, Belgin Medicina (Kaunas) Article Background and objectives: An important Non-Communicable Disease risk factor, hypertension (HT), is highly prevalent and controlled HT rates are not sufficient which increases the risk of developing premature deaths. The purpose of the study is to evaluate differences in all-cause and cardiovascular-related mortality according to HT status by using national data from Chronic Diseases and Risk Factors Survey in Turkey (2011–2017). Materials and Methods: Cox regression models were used to estimate hazard ratios (HR) for predicting the all-cause and cardiovascular system-related mortalities. Median follow-up period was 6.2 years. Results: Among individuals with HT, 41.8% was untreated, 30.1% received treatment and had controlled blood pressure, and 28.1% were under treatment but had uncontrolled BP levels. The hazard for mortality among treated & uncontrolled hypertensive participants was significantly higher for all-cause (HR = 1.32, 95% CI = 1.06–1.65), cardiovascular (HR = 2.11, 95% CI = 1.46–3.06), heart disease (HR = 2.24, 95% CI = 1.46–3.43), and Coronary Heart Disease mortality (HR = 2.66, 95% CI = 1.56–4.53) compared to normotensive participants. Conclusions: Individuals with HT who were treated but do not have controlled blood pressure in Turkey had a significantly increased risk of Cardiovascular Disease and all-cause mortality. Along with studies investigating the causes of uncontrolled blood pressure despite initiation of treatment, support should be provided to patients in cases of non-adherence to antihypertensive medication or life change recommendations. MDPI 2023-07-26 /pmc/articles/PMC10456768/ /pubmed/37629656 http://dx.doi.org/10.3390/medicina59081366 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sozmen, Kaan
Ergor, Gul
Sakarya, Sibel
Dinc Horasan, Gonul
Sahan, Ceyda
Ekinci, Banu
Arikan, Ahmet
Sis, Secil
Unal, Belgin
Evaluation of Blood Pressure Status and Mortality in Turkey: Findings from Chronic Diseases and Risk Factors Cohort Study
title Evaluation of Blood Pressure Status and Mortality in Turkey: Findings from Chronic Diseases and Risk Factors Cohort Study
title_full Evaluation of Blood Pressure Status and Mortality in Turkey: Findings from Chronic Diseases and Risk Factors Cohort Study
title_fullStr Evaluation of Blood Pressure Status and Mortality in Turkey: Findings from Chronic Diseases and Risk Factors Cohort Study
title_full_unstemmed Evaluation of Blood Pressure Status and Mortality in Turkey: Findings from Chronic Diseases and Risk Factors Cohort Study
title_short Evaluation of Blood Pressure Status and Mortality in Turkey: Findings from Chronic Diseases and Risk Factors Cohort Study
title_sort evaluation of blood pressure status and mortality in turkey: findings from chronic diseases and risk factors cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456768/
https://www.ncbi.nlm.nih.gov/pubmed/37629656
http://dx.doi.org/10.3390/medicina59081366
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