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Transcriptional regulation by the NSL complex enables diversification of IFT functions in ciliated versus nonciliated cells

Members of the NSL histone acetyltransferase complex are involved in multiorgan developmental syndromes. While the NSL complex is known for its importance in early development, its role in fully differentiated cells remains enigmatic. Using a kidney-specific model, we discovered that deletion of NSL...

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Detalles Bibliográficos
Autores principales: Tsang, Tsz Hong, Wiese, Meike, Helmstädter, Martin, Stehle, Thomas, Seyfferth, Janine, Shvedunova, Maria, Holz, Herbert, Walz, Gerd, Akhtar, Asifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456878/
https://www.ncbi.nlm.nih.gov/pubmed/37624894
http://dx.doi.org/10.1126/sciadv.adh5598