Immune microenvironment profiling of normal appearing colorectal mucosa biopsied over repeat patient visits reproducibly separates lynch syndrome patients based on their history of colon cancer

INTRODUCTION: Lynch syndrome (LS) is the most common hereditary cause of colorectal cancer (CRC), increasing lifetime risk of CRC by up to 70%. Despite this higher lifetime risk, disease penetrance in LS patients is highly variable and most LS patients undergoing CRC surveillance will not develop CR...

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Detalles Bibliográficos
Autores principales: Brand, Rhonda M., Dudley, Beth, Karloski, Eve, Zyhowski, Ashley, Raphael, Rebecca, Pitlor, Danielle, Metter, E. Jeffrey, Pai, Reet, Lee, Kenneth, Brand, Randall E., Uttam, Shikhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457127/
https://www.ncbi.nlm.nih.gov/pubmed/37637062
http://dx.doi.org/10.3389/fonc.2023.1174831

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