Single-cell multiomic analysis of thymocyte development reveals drivers of CD4(+) T cell and CD8(+) T cell lineage commitment

The development of CD4(+) T cells and CD8(+) T cells in the thymus is critical to adaptive immunity and is widely studied as a model of lineage commitment. Recognition of self-peptide major histocompatibility complex (MHC) class I or II by the T cell antigen receptor (TCR) determines the CD8(+) or C...

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Detalles Bibliográficos
Autores principales: Steier, Zoë, Aylard, Dominik A., McIntyre, Laura L., Baldwin, Isabel, Kim, Esther Jeong Yoon, Lutes, Lydia K., Ergen, Can, Huang, Tse-Shun, Robey, Ellen A., Yosef, Nir, Streets, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457207/
https://www.ncbi.nlm.nih.gov/pubmed/37580604
http://dx.doi.org/10.1038/s41590-023-01584-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457207/
https://www.ncbi.nlm.nih.gov/pubmed/37580604
http://dx.doi.org/10.1038/s41590-023-01584-0

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