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Electron counting detectors in scanning transmission electron microscopy via hardware signal processing
Transmission electron microscopy is a pivotal instrument in materials and biological sciences due to its ability to provide local structural and spectroscopic information on a wide range of materials. However, the electron detectors used in scanning transmission electron microscopy are often unable...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457289/ https://www.ncbi.nlm.nih.gov/pubmed/37626044 http://dx.doi.org/10.1038/s41467-023-40875-w |
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author | Peters, Jonathan J. P. Mullarkey, Tiarnan Hedley, Emma Müller, Karin H. Porter, Alexandra Mostaed, Ali Jones, Lewys |
author_facet | Peters, Jonathan J. P. Mullarkey, Tiarnan Hedley, Emma Müller, Karin H. Porter, Alexandra Mostaed, Ali Jones, Lewys |
author_sort | Peters, Jonathan J. P. |
collection | PubMed |
description | Transmission electron microscopy is a pivotal instrument in materials and biological sciences due to its ability to provide local structural and spectroscopic information on a wide range of materials. However, the electron detectors used in scanning transmission electron microscopy are often unable to provide quantified information, that is the number of electrons impacting the detector, without exhaustive calibration and processing. This results in arbitrary signal values with slow response times that cannot be used for quantification or comparison to simulations. Here we demonstrate and optimise a hardware signal processing approach to augment electron detectors to perform single electron counting. |
format | Online Article Text |
id | pubmed-10457289 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-104572892023-08-27 Electron counting detectors in scanning transmission electron microscopy via hardware signal processing Peters, Jonathan J. P. Mullarkey, Tiarnan Hedley, Emma Müller, Karin H. Porter, Alexandra Mostaed, Ali Jones, Lewys Nat Commun Article Transmission electron microscopy is a pivotal instrument in materials and biological sciences due to its ability to provide local structural and spectroscopic information on a wide range of materials. However, the electron detectors used in scanning transmission electron microscopy are often unable to provide quantified information, that is the number of electrons impacting the detector, without exhaustive calibration and processing. This results in arbitrary signal values with slow response times that cannot be used for quantification or comparison to simulations. Here we demonstrate and optimise a hardware signal processing approach to augment electron detectors to perform single electron counting. Nature Publishing Group UK 2023-08-25 /pmc/articles/PMC10457289/ /pubmed/37626044 http://dx.doi.org/10.1038/s41467-023-40875-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Peters, Jonathan J. P. Mullarkey, Tiarnan Hedley, Emma Müller, Karin H. Porter, Alexandra Mostaed, Ali Jones, Lewys Electron counting detectors in scanning transmission electron microscopy via hardware signal processing |
title | Electron counting detectors in scanning transmission electron microscopy via hardware signal processing |
title_full | Electron counting detectors in scanning transmission electron microscopy via hardware signal processing |
title_fullStr | Electron counting detectors in scanning transmission electron microscopy via hardware signal processing |
title_full_unstemmed | Electron counting detectors in scanning transmission electron microscopy via hardware signal processing |
title_short | Electron counting detectors in scanning transmission electron microscopy via hardware signal processing |
title_sort | electron counting detectors in scanning transmission electron microscopy via hardware signal processing |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457289/ https://www.ncbi.nlm.nih.gov/pubmed/37626044 http://dx.doi.org/10.1038/s41467-023-40875-w |
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