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Sex differences in airway volume and 3-dimensional shape in Japanese adults
(1) To establish normative data for three-dimensional (3D) measurements of the upper airway in young Japanese adults, and (2) to investigate sex-related differences in linear and volumetric measurements, as well as shape. This study employed cone-beam computed tomography (CBCT) images of 56 Japanese...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457298/ https://www.ncbi.nlm.nih.gov/pubmed/37626204 http://dx.doi.org/10.1038/s41598-023-41263-6 |
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author | Tanikawa, Chihiro Oka, Ayaka Shiraishi, Yuki Yamashiro, Takashi |
author_facet | Tanikawa, Chihiro Oka, Ayaka Shiraishi, Yuki Yamashiro, Takashi |
author_sort | Tanikawa, Chihiro |
collection | PubMed |
description | (1) To establish normative data for three-dimensional (3D) measurements of the upper airway in young Japanese adults, and (2) to investigate sex-related differences in linear and volumetric measurements, as well as shape. This study employed cone-beam computed tomography (CBCT) images of 56 Japanese young adults preselected from among 1000 patients, so that samples matched a historic 2D cephalometric cohort with normal occlusion using propensity score matching. Three-dimensional models of the oropharynx and hypopharynx were reconstructed from CBCT images and their volumes were calculated. We defined 20 landmarks on the surface of the 3D model and performed seven linear measurements between them. The mean and standard deviation of the linear measurements were calculated as the normative data for each sex as well as the volumes. Sex-related differences were analyzed using t-test (p < 0.05). Principal component discriminant analysis of the coordinate values of the landmarks was also performed to examine sex differences in shape. The normative ranges of the 3D measurements of the oropharynx and hypopharynx were determined according to sex. Sex-related differences in the measurement results were observed in hypopharyngeal length but not in volume. The hypopharynx length in males was significantly longer than that in females. The discriminant analysis showed that males tended to show longer and straight shapes, while females showed inversed triangular shapes from the frontal view. This result will allow clinicians to evaluate how patient airway characteristics differ from the normative 3D morphology of the upper airway. |
format | Online Article Text |
id | pubmed-10457298 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-104572982023-08-27 Sex differences in airway volume and 3-dimensional shape in Japanese adults Tanikawa, Chihiro Oka, Ayaka Shiraishi, Yuki Yamashiro, Takashi Sci Rep Article (1) To establish normative data for three-dimensional (3D) measurements of the upper airway in young Japanese adults, and (2) to investigate sex-related differences in linear and volumetric measurements, as well as shape. This study employed cone-beam computed tomography (CBCT) images of 56 Japanese young adults preselected from among 1000 patients, so that samples matched a historic 2D cephalometric cohort with normal occlusion using propensity score matching. Three-dimensional models of the oropharynx and hypopharynx were reconstructed from CBCT images and their volumes were calculated. We defined 20 landmarks on the surface of the 3D model and performed seven linear measurements between them. The mean and standard deviation of the linear measurements were calculated as the normative data for each sex as well as the volumes. Sex-related differences were analyzed using t-test (p < 0.05). Principal component discriminant analysis of the coordinate values of the landmarks was also performed to examine sex differences in shape. The normative ranges of the 3D measurements of the oropharynx and hypopharynx were determined according to sex. Sex-related differences in the measurement results were observed in hypopharyngeal length but not in volume. The hypopharynx length in males was significantly longer than that in females. The discriminant analysis showed that males tended to show longer and straight shapes, while females showed inversed triangular shapes from the frontal view. This result will allow clinicians to evaluate how patient airway characteristics differ from the normative 3D morphology of the upper airway. Nature Publishing Group UK 2023-08-25 /pmc/articles/PMC10457298/ /pubmed/37626204 http://dx.doi.org/10.1038/s41598-023-41263-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Tanikawa, Chihiro Oka, Ayaka Shiraishi, Yuki Yamashiro, Takashi Sex differences in airway volume and 3-dimensional shape in Japanese adults |
title | Sex differences in airway volume and 3-dimensional shape in Japanese adults |
title_full | Sex differences in airway volume and 3-dimensional shape in Japanese adults |
title_fullStr | Sex differences in airway volume and 3-dimensional shape in Japanese adults |
title_full_unstemmed | Sex differences in airway volume and 3-dimensional shape in Japanese adults |
title_short | Sex differences in airway volume and 3-dimensional shape in Japanese adults |
title_sort | sex differences in airway volume and 3-dimensional shape in japanese adults |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457298/ https://www.ncbi.nlm.nih.gov/pubmed/37626204 http://dx.doi.org/10.1038/s41598-023-41263-6 |
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