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Targeted inhibition of protein synthesis renders cancer cells vulnerable to apoptosis by unfolded protein response

Cellular stress responses including the unfolded protein response (UPR) decide over the fate of an individual cell to ensure survival of the entire organism. During physiologic UPR counter-regulation, protective proteins are upregulated to prevent cell death. A similar strategy induces resistance to...

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Detalles Bibliográficos
Autores principales: Gsottberger, Franziska, Meier, Christina, Ammon, Anna, Parker, Scott, Wendland, Kerstin, George, Rebekka, Petkovic, Srdjan, Mellenthin, Lisa, Emmerich, Charlotte, Lutzny-Geier, Gloria, Metzler, Markus, Mackensen, Andreas, Chandramohan, Vidyalakshmi, Müller, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457359/
https://www.ncbi.nlm.nih.gov/pubmed/37626037
http://dx.doi.org/10.1038/s41419-023-06055-w