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Targeted inhibition of protein synthesis renders cancer cells vulnerable to apoptosis by unfolded protein response
Cellular stress responses including the unfolded protein response (UPR) decide over the fate of an individual cell to ensure survival of the entire organism. During physiologic UPR counter-regulation, protective proteins are upregulated to prevent cell death. A similar strategy induces resistance to...
Autores principales: | Gsottberger, Franziska, Meier, Christina, Ammon, Anna, Parker, Scott, Wendland, Kerstin, George, Rebekka, Petkovic, Srdjan, Mellenthin, Lisa, Emmerich, Charlotte, Lutzny-Geier, Gloria, Metzler, Markus, Mackensen, Andreas, Chandramohan, Vidyalakshmi, Müller, Fabian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457359/ https://www.ncbi.nlm.nih.gov/pubmed/37626037 http://dx.doi.org/10.1038/s41419-023-06055-w |
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