LZTR1 deficiency exerts high metastatic potential by enhancing sensitivity to EMT induction and controlling KLHL12-mediated collagen secretion

Leucine zipper-like transcriptional regulator 1 (LZTR1), a substrate adaptor of Cullin 3 (CUL3)-based E3 ubiquitin ligase, regulates proteostasis of the RAS subfamily. Mutations in LZTR1 have been identified in patients with several types of cancer. However, the role of LZTR1 in tumor metastasis and...

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Detalles Bibliográficos
Autores principales: Abe, Taiki, Kanno, Shin-ichiro, Niihori, Tetsuya, Terao, Miho, Takada, Shuji, Aoki, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457367/
https://www.ncbi.nlm.nih.gov/pubmed/37626065
http://dx.doi.org/10.1038/s41419-023-06072-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457367/
https://www.ncbi.nlm.nih.gov/pubmed/37626065
http://dx.doi.org/10.1038/s41419-023-06072-9

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