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Novel VEGFR2 inhibitors with thiazoloquinoxaline scaffold targeting hepatocellular carcinoma with lower cardiotoxic impact

Hepatocellular carcinoma (HCC) is a fatal tumor which is usually diagnosed at advanced stage. Molecular targeted drugs were used recently to treat HCC, however, due to serious side effects, mainly cardiotoxicity and emergence of resistance, there is demanding to explore new chemotherapeutics. 10 nov...

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Detalles Bibliográficos
Autores principales: El-Hazek, Reham M. M., Zaher, Nashwa H., El-Gazzar, Mostafa G. M., Fadel, Noha A., El-Sabbagh, Walaa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457369/
https://www.ncbi.nlm.nih.gov/pubmed/37626064
http://dx.doi.org/10.1038/s41598-023-40832-z