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Novel VEGFR2 inhibitors with thiazoloquinoxaline scaffold targeting hepatocellular carcinoma with lower cardiotoxic impact
Hepatocellular carcinoma (HCC) is a fatal tumor which is usually diagnosed at advanced stage. Molecular targeted drugs were used recently to treat HCC, however, due to serious side effects, mainly cardiotoxicity and emergence of resistance, there is demanding to explore new chemotherapeutics. 10 nov...
Autores principales: | El-Hazek, Reham M. M., Zaher, Nashwa H., El-Gazzar, Mostafa G. M., Fadel, Noha A., El-Sabbagh, Walaa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457369/ https://www.ncbi.nlm.nih.gov/pubmed/37626064 http://dx.doi.org/10.1038/s41598-023-40832-z |
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