Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab′)(2) fragments

The development of new therapies against SARS-CoV-2 is required to extend the toolkit of intervention strategies to combat the global pandemic. In this study, hyperimmune plasma from sheep immunised with whole spike SARS-CoV-2 recombinant protein has been used to generate candidate products. In addi...

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Detalles Bibliográficos
Autores principales: Findlay-Wilson, Stephen, Easterbrook, Linda, Smith, Sandra, Pope, Neville, Aldridge, Matthew, Humphries, Gareth, Schuhmann, Holger, Ngabo, Didier, Rayner, Emma, Otter, Ashley, Coleman, Thomas, Hicks, Bethany, Halkerston, Rachel, Apostolakis, Kostis, Taylor, Stephen, Fotheringham, Susan, Horton, Amanda, CanoCejas, Irene, Wand, Matthew, Tree, Julia A., Sutton, Mark, Graham, Victoria, Hewson, Roger, Dowall, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457378/
https://www.ncbi.nlm.nih.gov/pubmed/37626085
http://dx.doi.org/10.1038/s41598-023-40277-4

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