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Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models

Metastasis is the leading cause of mortality in cancer patients. L-type amino acid transporter 1 (LAT1, SLC7A5) is a Na(+)-independent neutral amino acid transporter highly expressed in various cancers to support their growth. Although high LAT1 expression is closely associated with cancer metastasi...

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Detalles Bibliográficos
Autores principales:	Shi, Zitong, Kaneda-Nakashima, Kazuko, Ohgaki, Ryuichi, Xu, Minhui, Okanishi, Hiroki, Endou, Hitoshi, Nagamori, Shushi, Kanai, Yoshikatsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457391/ https://www.ncbi.nlm.nih.gov/pubmed/37626086 http://dx.doi.org/10.1038/s41598-023-41096-3

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