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Metal-ion transporter SLC39A8 is required for brain manganese uptake and accumulation

Manganese (Mn) is an essential nutrient, but is toxic in excess. Whole-body Mn levels are regulated in part by the metal-ion influx transporter SLC39A8, which plays an essential role in the liver by reclaiming Mn from bile. Physiological roles of SLC39A8 in Mn homeostasis in other tissues, however,...

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Detalles Bibliográficos
Autores principales:	Liu, Qingli, Jenkitkasemwong, Supak, Prami, Tamanna Afrin, McCabe, Shannon Morgan, Zhao, Ningning, Hojyo, Shintaro, Fukada, Toshiyuki, Knutson, Mitchell D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457451/ https://www.ncbi.nlm.nih.gov/pubmed/37482277 http://dx.doi.org/10.1016/j.jbc.2023.105078

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