Cargando…

Anomaly detection in mixed high-dimensional molecular data

MOTIVATION: Mixed molecular data combines continuous and categorical features of the same samples, such as OMICS profiles with genotypes, diagnoses, or patient sex. Like all high-dimensional molecular data, it is prone to incorrect values that can stem from various sources for example the technical...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buck, Lena, Schmidt, Tobias, Feist, Maren, Schwarzfischer, Philipp, Kube, Dieter, Oefner, Peter J, Zacharias, Helena U, Altenbuchinger, Michael, Dettmer, Katja, Gronwald, Wolfram, Spang, Rainer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457663/ https://www.ncbi.nlm.nih.gov/pubmed/37584673 http://dx.doi.org/10.1093/bioinformatics/btad501

Ejemplares similares

Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression
por: Feist, Maren, et al.
Publicado: (2018)

An R-Package for the Deconvolution and Integration of 1D NMR Data: MetaboDecon1D
por: Häckl, Martina, et al.
Publicado: (2021)

A multi-source data integration approach reveals novel associations between metabolites and renal outcomes in the German Chronic Kidney Disease study
por: Altenbuchinger, Michael, et al.
Publicado: (2019)

Statistical Analysis of NMR Metabolic Fingerprints: Established Methods and Recent Advances
por: Zacharias, Helena U., et al.
Publicado: (2018)

Platform independent protein-based cell-of-origin subtyping of diffuse large B-cell lymphoma in formalin-fixed paraffin-embedded tissue
por: Reinders, Jörg, et al.
Publicado: (2020)

BITES: balanced individual treatment effect for survival data
por: Schrod, S, et al.
Publicado: (2022)

Molecular signatures that can be transferred across different omics platforms
por: Altenbuchinger, M, et al.
Publicado: (2017)

Bucket Fuser: Statistical Signal Extraction for 1D (1)H NMR Metabolomic Data
por: Altenbuchinger, Michael, et al.
Publicado: (2022)

Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma
por: Kleo, Karsten, et al.
Publicado: (2019)

High CD206 levels in Hodgkin lymphoma‐educated macrophages are linked to matrix‐remodeling and lymphoma dissemination
por: Arlt, Annekatrin, et al.
Publicado: (2020)

Isotope Ratio Outlier Analysis (IROA) for HPLC–TOFMS-Based Metabolomics of Human Urine
por: Fadil, Fadi, et al.
Publicado: (2022)

State-of-the art data normalization methods improve NMR-based metabolomic analysis
por: Kohl, Stefanie M., et al.
Publicado: (2011)

Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR
por: Heinrich, Paul, et al.
Publicado: (2018)

DTD: An R Package for Digital Tissue Deconvolution
por: Schön, Marian, et al.
Publicado: (2020)

Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models
por: Pirkl, Martin, et al.
Publicado: (2016)

From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function
por: Sekula, Peggy, et al.
Publicado: (2017)

Systematic Evaluation of Non-Uniform Sampling Parameters in the Targeted Analysis of Urine Metabolites by (1)H,(1)H 2D NMR Spectroscopy
por: Schlippenbach, Trixi von, et al.
Publicado: (2018)

Robust Metabolite Quantification from J-Compensated 2D (1)H-(13)C-HSQC Experiments
por: Weitzel, Alexander, et al.
Publicado: (2020)

Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data
por: Schrader, Alexandra, et al.
Publicado: (2016)

Visceral adipose tissue but not subcutaneous adipose tissue is associated with urine and serum metabolites
por: Schlecht, Inga, et al.
Publicado: (2017)

Automated macrophage counting in DLBCL tissue samples: a ROF filter based approach
por: Wagner, Marcus, et al.
Publicado: (2019)

Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models
por: Tauber, Philipp, et al.
Publicado: (2021)

Characterization of the Methylthioadenosine Phosphorylase Polymorphism rs7023954 - Incidence and Effects on Enzymatic Function in Malignant Melanoma
por: Limm, Katharina, et al.
Publicado: (2016)

Chronic Kidney Disease Cohort Studies: A Guide to Metabolome Analyses
por: Schultheiss, Ulla T., et al.
Publicado: (2021)

Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite
por: Berger, Raffaela S., et al.
Publicado: (2021)

New Aspects of an Old Drug – Diclofenac Targets MYC and Glucose Metabolism in Tumor Cells
por: Gottfried, Eva, et al.
Publicado: (2013)

ReseqChip: Automated integration of multiple local context probe data from the MitoChip array in mitochondrial DNA sequence assembly
por: Thieme, Marian, et al.
Publicado: (2009)

Degradation of D-2-hydroxyglutarate in the presence of isocitrate dehydrogenase mutations
por: Berger, Raffaela S., et al.
Publicado: (2019)

Optimized Protocol for the In Situ Derivatization of Glutathione with N-Ethylmaleimide in Cultured Cells and the Simultaneous Determination of Glutathione/Glutathione Disulfide Ratio by HPLC-UV-QTOF-MS
por: Sun, Xueni, et al.
Publicado: (2020)

Antithymocyte Globulin Induces a Tolerogenic Phenotype in Human Dendritic Cells
por: Roider, Tobias, et al.
Publicado: (2016)

Cold Atmospheric Plasma Changes the Amino Acid Composition of Solutions and Influences the Anti-Tumor Effect on Melanoma Cells
por: Arndt, Stephanie, et al.
Publicado: (2021)

Anomalies and supersymmetric regularization by dimensional reduction
por: Nicolai, Hermann C, et al.
Publicado: (1980)

Serotonin and tryptophan metabolites, autoantibodies and gut microbiome in APECED
por: Naskali, Emmi, et al.
Publicado: (2019)

Adjusting microbiome profiles for differences in microbial load by spike-in bacteria
por: Stämmler, Frank, et al.
Publicado: (2016)

Bovine blood derived macrophages are unable to control Coxiella burnetii replication under hypoxic conditions
por: Mauermeir, Michael, et al.
Publicado: (2023)

The virial expansion and the two-dimensional axial anomaly
por: Comtet, A, et al.
Publicado: (1989)

Anomalies and effective actions in two-dimensional superspace
por: Delduc, F, et al.
Publicado: (1992)

Implications of anomalies in two-dimensional vector models
por: Elitzur, Shmuel, et al.
Publicado: (1981)

Two-and four-dimensional anomalies with an instanton background
por: Forte, Stefano
Publicado: (1986)

Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism
por: Leisz, Sandra, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_jo46j9j8sjj32nmsv4dk77kbm8