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Targeted Glioblastoma Treatment via Synthesis and Functionalization of Gold Nanoparticles With De Novo–Engineered Transferrin-Like Peptides: Protocol for a Novel Method

BACKGROUND: Glioblastoma multiforme (GBM) is an aggressive brain tumor with limited treatment options due to the blood-brain barrier’s (BBB’s) impedance and inherent resistance to chemotherapy. Gold nanoparticles (AuNPs) functionalized with transferrin-like peptides show promise in overcoming these...

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Detalles Bibliográficos
Autores principales: Müller Fiedler, Augusto, Medeiros, Michelle, Fiedler, Haidi Dalinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457702/
https://www.ncbi.nlm.nih.gov/pubmed/37531222
http://dx.doi.org/10.2196/49417