Design, Synthesis and Biological Evaluation of Novel PEG-Rakicidin B1 Hybrid as Clostridium difficile (CD) Targeted Anti-Bacterial Agent

Rakicidin B1 was isolated and purified from the culture broth of a marine Streptomyces sp. as a potent anti-cancer agent, and lately the compound and its derivatives have firstly been found to possess anti-Clostridium difficile (CD) activity but with high cytotoxicity. Herein, following our previous...

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Detalles Bibliográficos
Autores principales: Xie, Lijun, Chen, Li, Wei, Yongbo, Chen, Nannan, Wu, Tong, Zhou, Jingming, Jiang, Hong, Lin, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457740/
https://www.ncbi.nlm.nih.gov/pubmed/37630404
http://dx.doi.org/10.3390/molecules28166152

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