Antiprotozoal Activity of Benzoylthiourea Derivatives against Trypanosoma cruzi: Insights into Mechanism of Action

For decades, only two nitroheterocyclic drugs have been used as therapeutic agents for Chagas disease. However, these drugs present limited effectiveness during the chronic phase, possess unfavorable pharmacokinetic properties, and induce severe adverse effects, resulting in low treatment adherence....

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Detalles Bibliográficos
Autores principales: Pereira, Patrícia Morais Lopes, Fernandes, Bruna Terci, dos Santos, Vitória Ribeiro, Cabral, Weslei Roberto Correia, Lovo-Martins, Maria Isabel, Alonso, Lais, Lancheros, César Armando Contreras, de Paula, Jéssica Carreira, Camargo, Priscila Goes, Suzukawa, Helena Tiemi, Alonso, Antônio, Macedo, Fernando, Nakamura, Celso Vataru, Tavares, Eliandro Reis, de Lima Ferreira Bispo, Marcelle, Yamauchi, Lucy Megumi, Pinge-Filho, Phileno, Yamada-Ogatta, Sueli Fumie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457850/
https://www.ncbi.nlm.nih.gov/pubmed/37623972
http://dx.doi.org/10.3390/pathogens12081012

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