Development of Liposome Systems for Enhancing the PK Properties of Bivalent PROTACs

Proteolysis-Targeting Chimeras (PROTACs) are a promising new technology in drug development. They have rapidly evolved in recent years, with several of them in clinical trials. While most of these advances have been associated with monovalent protein degraders, bivalent PROTACs have also entered cli...

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Detalles Bibliográficos
Autores principales: Kou, Ponien, Levy, Elizabeth S., Nguyen, An D., Zhang, Donglu, Chen, Shu, Cui, Yusi, Zhang, Xing, Broccatelli, Fabio, Pizzano, Jennifer, Cantley, Jennifer, Bortolon, Elizabeth, Rousseau, Emma, Berlin, Michael, Dragovich, Peter, Sethuraman, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458015/
https://www.ncbi.nlm.nih.gov/pubmed/37631312
http://dx.doi.org/10.3390/pharmaceutics15082098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458015/
https://www.ncbi.nlm.nih.gov/pubmed/37631312
http://dx.doi.org/10.3390/pharmaceutics15082098

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