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The Immunogenicity and Properties of a Whole-Cell ETEC Vaccine Inactivated with Psoralen and UVA Light in Comparison to Formalin

Inactivated whole-cell vaccines present a full repertoire of antigens to the immune system. Formalin treatment, a standard method for microbial inactivation, can modify or destroy protein antigenic epitopes. We tested the hypothesis that photochemical inactivation with psoralen and UVA light (PUVA),...

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Detalles Bibliográficos
Autores principales: Westcott, Marlena M., Blevins, Maria, Wierzba, Thomas F., Morse, Alexis E., White, Kinnede R., Sanders, Leigh Ann, Sanders, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458022/
https://www.ncbi.nlm.nih.gov/pubmed/37630600
http://dx.doi.org/10.3390/microorganisms11082040