Nanostructured Lipid Carriers to Enhance the Bioavailability and Solubility of Ranolazine: Statistical Optimization and Pharmacological Evaluations

Chronic stable angina pectoris is the primary indication for ranolazine (RZ), an anti-anginal drug. The drug has an anti-ischemic action that is unaffected by either blood pressure or heart rate. Due to the first-pass effect, the drug has a reduced bioavailability of 35 to 50%. The study emphasized...

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Detalles Bibliográficos
Autores principales: Unnisa, Aziz, Chettupalli, Ananda K., Alazragi, Reem S., Alelwani, Walla, Bannunah, Azzah M., Barnawi, Jameel, Amarachinta, Padmanabha R., Jandrajupalli, Suresh B., Elamine, Badria A., Mohamed, Omkalthoum A., Hussain, Talib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458271/
https://www.ncbi.nlm.nih.gov/pubmed/37631066
http://dx.doi.org/10.3390/ph16081151

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