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Novel nasal niosomes loaded with lacosamide and coated with chitosan: A possible pathway to target the brain to control partial-onset seizures

This work aimed to develop and produce lacosamide-loaded niosomes coated with chitosan (LCA-CTS-NSM) using a thin-film hydration method and the Box-Behnken design. The effect of three independent factors (Span 60 amount, chitosan concentration, and cholesterol amount) on vesicle size, entrapment eff...

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Detalles Bibliográficos
Autores principales:	Tulbah, Alaa S., Elkomy, Mohammed H., Zaki, Randa Mohammed, Eid, Hussein M., Eissa, Essam M., Ali, Adel A., Yassin, Heba A., Aldosari, Basmah Nasser, Naguib, Ibrahim A., Hassan, Amira H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458293/ https://www.ncbi.nlm.nih.gov/pubmed/37637477 http://dx.doi.org/10.1016/j.ijpx.2023.100206

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