Cargando…

Fatal Overdose with the Cannabinoid Receptor Agonists MDMB-4en-PINACA and 4F-ABUTINACA: A Case Report and Review of the Literature

A case of a 26-year-old male who died from consuming synthetic cannabinoid receptor agonists MDMB-4en-PINACA and 4F-ABUTINACA is reported. MDMB-4en-PINACA and 4F-ABUTINACA are potent synthetic cannabinoid receptor agonists (SCRAs). This is the first detailed reporting of MDMB-4-en-PINACA and 4F-ABUT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Simon, Gábor, Kuzma, Mónika, Mayer, Mátyás, Petrus, Karola, Tóth, Dénes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458319/ https://www.ncbi.nlm.nih.gov/pubmed/37624178 http://dx.doi.org/10.3390/toxics11080673

Ejemplares similares

Simultaneous fatal poisoning of two victims with 4F-MDMB-BINACA and ethanol
por: Simon, Gábor, et al.
Publicado: (2022)

Heroin Adulterated with the Novel Synthetic Cannabinoid, 5F-MDMB-PINACA: A Case Series
por: Ershad, Muhammed, et al.
Publicado: (2020)

Detection of the Synthetic Cannabinoids AB-CHMINACA, ADB-CHMINACA, MDMB-CHMICA, and 5F-MDMB-PINACA in Biological Matrices: A Systematic Review
por: Navarro-Tapia, Elisabet, et al.
Publicado: (2022)

Analytical findings in a non-fatal intoxication with the synthetic cannabinoid 5F-ADB (5F-MDMB-PINACA): a case report
por: Gaunitz, Franziska, et al.
Publicado: (2021)

Correction to: Analytical findings in a non-fatal intoxication with the synthetic cannabinoid 5F-ADB (5F-MDMB-PINACA): a case report
por: Gaunitz, Franziska, et al.
Publicado: (2022)

Characterization of the synthetic cannabinoid MDMB-CHMCZCA
por: Weber, Carina, et al.
Publicado: (2016)

Fatal intoxication with new synthetic cannabinoids 5F-MDMB-PICA and 4F-MDMB-BINACA—parent compounds and metabolite identification in blood, urine and cerebrospinal fluid
por: Tokarczyk, Bogdan, et al.
Publicado: (2022)

Synthesis and pharmacological evaluation of newly detected synthetic cannabinoid receptor agonists AB-4CN-BUTICA, MMB-4CN-BUTINACA, MDMB-4F-BUTICA, MDMB-4F-BUTINACA and their analogs
por: Sparkes, Eric, et al.
Publicado: (2022)

Neurochemical and Behavioral Characterization after Acute and Repeated Exposure to Novel Synthetic Cannabinoid Agonist 5-MDMB-PICA
por: Musa, Aurora, et al.
Publicado: (2020)

Off-target pharmacological profiling of synthetic cannabinoid receptor agonists including AMB-FUBINACA, CUMYL-PINACA, PB-22, and XLR-11
por: Kevin, Richard C., et al.
Publicado: (2022)

The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB-FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activities
por: Longworth, Mitchell, et al.
Publicado: (2016)

Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism
por: Park, Yu Mi, et al.
Publicado: (2022)

5F-Cumyl-PINACA in ‘e-liquids’ for electronic cigarettes: comprehensive characterization of a new type of synthetic cannabinoid in a trendy product including investigations on the in vitro and in vivo phase I metabolism of 5F-Cumyl-PINACA and its non-fluorinated analog Cumyl-PINACA
por: Angerer, Verena, et al.
Publicado: (2018)

Inhibitory Effect of AB-PINACA, Indazole Carboxamide Synthetic Cannabinoid, on Human Major Drug-Metabolizing Enzymes and Transporters
por: Park, Eun Jeong, et al.
Publicado: (2020)

Cytotoxicity, metabolism, and isozyme mapping of the synthetic cannabinoids JWH-200, A-796260, and 5F-EMB-PINACA studied by means of in vitro systems
por: Gampfer, Tanja M., et al.
Publicado: (2021)

Detection of a New Tert-Leucinate Synthetic Cannabinoid 5F-MDMB-PICA and Its Metabolites in Human Hair: Application to Authentic Cases
por: Shi, Yan, et al.
Publicado: (2020)

Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ(9)-THC
por: Hutchison, Rachel D., et al.
Publicado: (2018)

Analytically Confirmed Intoxications Involving MDMB-CHMICA from the STRIDA Project
por: Bäckberg, Matilda, et al.
Publicado: (2016)

Drug involvement in fatal overdoses
por: Ruhm, Christopher J.
Publicado: (2017)

Characteristics of fatal insulin overdoses
por: Stephenson, Lilli, et al.
Publicado: (2022)

Detection of Fatal Potassium Overdose: A Case Report and Review of the Literature
por: Simon, Gábor
Publicado: (2023)

Analytical Methodologies for the Characterization and Analysis of the Parent Compound and Phase I Metabolites of 4F-MDMB-BICA in Human Microsome, Urine and Blood Samples
por: Körmöczi, Tímea, et al.
Publicado: (2021)

Fatal overdose of iron tablets in adults
por: Abhilash, Kundavaram P. P., et al.
Publicado: (2013)

Fatal Overdose Surveillance in the Commonwealth of Pennsylvania
por: Costigan, Craig, et al.
Publicado: (2019)

Understanding Fatal and Non-Fatal Drug Overdose Risk Factors: Overdose Risk Questionnaire Pilot Study—Validation
por: Doggui, Radhouene, et al.
Publicado: (2021)

Cannabinoid(1) (CB-1) receptor antagonists: a molecular approach to treating acute cannabinoid overdose
por: Skolnick, Phil, et al.
Publicado: (2019)

Fatal Metformin Overdose Presenting with Progressive Hyperglycemia
por: Suchard, Jeffrey R., et al.
Publicado: (2008)

The Effect of Naloxone Access Laws on Fatal Synthetic Opioid Overdose Fatality Rates
por: Tabatabai, Mohammad, et al.
Publicado: (2023)

Multiple imputation of missing data in multilevel models with the R package mdmb: a flexible sequential modeling approach
por: Grund, Simon, et al.
Publicado: (2021)

CUMYL-4CN-BINACA Is an Efficacious and Potent Pro-Convulsant Synthetic Cannabinoid Receptor Agonist
por: Kevin, Richard C., et al.
Publicado: (2019)

Fatal Transdermal Fentanyl Patch Overdose in a Child
por: Hilado, Mark A, et al.
Publicado: (2020)

Risk markers for fatal and non-fatal prescription drug overdose: a meta-analysis
por: Brady, Joanne E., et al.
Publicado: (2017)

Concentrations of psychoactive substances in blood samples from non‐fatal and fatal opioid overdoses
por: Edvardsen, Hilde Marie Erøy, et al.
Publicado: (2022)

Surveillance of a Synthetic Cannabinoid Overdose Outbreak using Syndromic & EMS Data
por: Rock, Peter J., et al.
Publicado: (2018)

Exploring determinants of agonist efficacy at the CB1 cannabinoid receptor: Analogues of the synthetic cannabinoid receptor agonist EG‐018
por: Finlay, David B., et al.
Publicado: (2022)

Motor vehicle collisions caused by the ‘super-strength’ synthetic cannabinoids, MAM-2201, 5F-PB-22, 5F-AB-PINACA, 5F-AMB and 5F-ADB in Japan experienced from 2012 to 2014
por: Kaneko, Shuji
Publicado: (2017)

Effect of Prescriber Notifications of Patient’s Fatal Overdose on Opioid Prescribing at 4 to 12 Months: A Randomized Clinical Trial
por: Doctor, Jason N., et al.
Publicado: (2023)

Cannabinoids: A New Group of Agonists of PPARs
por: Sun, Yan, et al.
Publicado: (2007)

A Social Gradient in Fatal Opioids and Cocaine Related Overdoses?
por: Origer, Alain, et al.
Publicado: (2015)

Fatal Overdose due to Confusion of an Transdermal Fentanyl Delivery System
por: Voigt, Ingo
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_6kknf4duel1orhfdlufgkiac6p