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Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework

(1) Background: To investigate the grouping of obesity and insulin resistance with caries and periodontitis from a syndemic perspective through pathways of socioeconomic inequalities, smoking, alcohol, and high sugar consumption in adolescence. (2) Methods: The population-based RPS Cohort study, São...

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Autores principales: Ladeira, Lorena Lúcia Costa, Nascimento, Gustavo Giacomelli, Leite, Fábio Renato Manzolli, Alves-Costa, Silas, Barbosa, Janaína Maiana Abreu, Alves, Claudia Maria Coelho, Thomaz, Erika Barbara Abreu Fonseca, Batista, Rosangela Fernandes Lucena, Ribeiro, Cecilia Claudia Costa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458482/
https://www.ncbi.nlm.nih.gov/pubmed/37630703
http://dx.doi.org/10.3390/nu15163512
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author Ladeira, Lorena Lúcia Costa
Nascimento, Gustavo Giacomelli
Leite, Fábio Renato Manzolli
Alves-Costa, Silas
Barbosa, Janaína Maiana Abreu
Alves, Claudia Maria Coelho
Thomaz, Erika Barbara Abreu Fonseca
Batista, Rosangela Fernandes Lucena
Ribeiro, Cecilia Claudia Costa
author_facet Ladeira, Lorena Lúcia Costa
Nascimento, Gustavo Giacomelli
Leite, Fábio Renato Manzolli
Alves-Costa, Silas
Barbosa, Janaína Maiana Abreu
Alves, Claudia Maria Coelho
Thomaz, Erika Barbara Abreu Fonseca
Batista, Rosangela Fernandes Lucena
Ribeiro, Cecilia Claudia Costa
author_sort Ladeira, Lorena Lúcia Costa
collection PubMed
description (1) Background: To investigate the grouping of obesity and insulin resistance with caries and periodontitis from a syndemic perspective through pathways of socioeconomic inequalities, smoking, alcohol, and high sugar consumption in adolescence. (2) Methods: The population-based RPS Cohort study, São Luís, Brazil, in ages 18–19 years (n = 2515) was used. The outcomes were the grouping of pbesity and Insulin Resistance Phenotype (latent variable formed by Triglycerides/HDL ratio, TyG index, and VLDL) and the Chronic Oral Disease Burden (latent variable comprising caries, bleeding on probing, probing depth ≥ 4 mm, clinical attachment level ≥ 3 mm, and visible plaque index ≥ 15%). Socioeconomic Inequalities influencing the Behavioral Risk Factors (latent variable formed by added sugar, smoking, and alcohol) were analyzed using structural equation modeling. (3) Results: Socioeconomic Inequalities were associated with the Chronic Oral Disease Burden [Standardized Coefficient (SC) = 0.222, p < 0.001]. Behavioral Risk Factors were associated with increased Chronic Oral Disease Burden (SC = 0.103; p = 0.013). Obesity was associated with the Insulin Resistance Phenotype (SC = 0.072; p < 0.001) and the Chronic Oral Disease Burden (SC = 0.066; p = 0.005). The Insulin Resistance Phenotype and the Chronic Oral Disease Burden were associated (SC = 0.053; p = 0.032). (4) Conclusion: The grouping of obesity and early events of diabetes with caries and periodontitis call for a syndemic approach in adolescence.
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spelling pubmed-104584822023-08-27 Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework Ladeira, Lorena Lúcia Costa Nascimento, Gustavo Giacomelli Leite, Fábio Renato Manzolli Alves-Costa, Silas Barbosa, Janaína Maiana Abreu Alves, Claudia Maria Coelho Thomaz, Erika Barbara Abreu Fonseca Batista, Rosangela Fernandes Lucena Ribeiro, Cecilia Claudia Costa Nutrients Article (1) Background: To investigate the grouping of obesity and insulin resistance with caries and periodontitis from a syndemic perspective through pathways of socioeconomic inequalities, smoking, alcohol, and high sugar consumption in adolescence. (2) Methods: The population-based RPS Cohort study, São Luís, Brazil, in ages 18–19 years (n = 2515) was used. The outcomes were the grouping of pbesity and Insulin Resistance Phenotype (latent variable formed by Triglycerides/HDL ratio, TyG index, and VLDL) and the Chronic Oral Disease Burden (latent variable comprising caries, bleeding on probing, probing depth ≥ 4 mm, clinical attachment level ≥ 3 mm, and visible plaque index ≥ 15%). Socioeconomic Inequalities influencing the Behavioral Risk Factors (latent variable formed by added sugar, smoking, and alcohol) were analyzed using structural equation modeling. (3) Results: Socioeconomic Inequalities were associated with the Chronic Oral Disease Burden [Standardized Coefficient (SC) = 0.222, p < 0.001]. Behavioral Risk Factors were associated with increased Chronic Oral Disease Burden (SC = 0.103; p = 0.013). Obesity was associated with the Insulin Resistance Phenotype (SC = 0.072; p < 0.001) and the Chronic Oral Disease Burden (SC = 0.066; p = 0.005). The Insulin Resistance Phenotype and the Chronic Oral Disease Burden were associated (SC = 0.053; p = 0.032). (4) Conclusion: The grouping of obesity and early events of diabetes with caries and periodontitis call for a syndemic approach in adolescence. MDPI 2023-08-09 /pmc/articles/PMC10458482/ /pubmed/37630703 http://dx.doi.org/10.3390/nu15163512 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ladeira, Lorena Lúcia Costa
Nascimento, Gustavo Giacomelli
Leite, Fábio Renato Manzolli
Alves-Costa, Silas
Barbosa, Janaína Maiana Abreu
Alves, Claudia Maria Coelho
Thomaz, Erika Barbara Abreu Fonseca
Batista, Rosangela Fernandes Lucena
Ribeiro, Cecilia Claudia Costa
Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework
title Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework
title_full Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework
title_fullStr Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework
title_full_unstemmed Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework
title_short Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework
title_sort obesity, insulin resistance, caries, and periodontitis: syndemic framework
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458482/
https://www.ncbi.nlm.nih.gov/pubmed/37630703
http://dx.doi.org/10.3390/nu15163512
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