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Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework
(1) Background: To investigate the grouping of obesity and insulin resistance with caries and periodontitis from a syndemic perspective through pathways of socioeconomic inequalities, smoking, alcohol, and high sugar consumption in adolescence. (2) Methods: The population-based RPS Cohort study, São...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458482/ https://www.ncbi.nlm.nih.gov/pubmed/37630703 http://dx.doi.org/10.3390/nu15163512 |
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author | Ladeira, Lorena Lúcia Costa Nascimento, Gustavo Giacomelli Leite, Fábio Renato Manzolli Alves-Costa, Silas Barbosa, Janaína Maiana Abreu Alves, Claudia Maria Coelho Thomaz, Erika Barbara Abreu Fonseca Batista, Rosangela Fernandes Lucena Ribeiro, Cecilia Claudia Costa |
author_facet | Ladeira, Lorena Lúcia Costa Nascimento, Gustavo Giacomelli Leite, Fábio Renato Manzolli Alves-Costa, Silas Barbosa, Janaína Maiana Abreu Alves, Claudia Maria Coelho Thomaz, Erika Barbara Abreu Fonseca Batista, Rosangela Fernandes Lucena Ribeiro, Cecilia Claudia Costa |
author_sort | Ladeira, Lorena Lúcia Costa |
collection | PubMed |
description | (1) Background: To investigate the grouping of obesity and insulin resistance with caries and periodontitis from a syndemic perspective through pathways of socioeconomic inequalities, smoking, alcohol, and high sugar consumption in adolescence. (2) Methods: The population-based RPS Cohort study, São Luís, Brazil, in ages 18–19 years (n = 2515) was used. The outcomes were the grouping of pbesity and Insulin Resistance Phenotype (latent variable formed by Triglycerides/HDL ratio, TyG index, and VLDL) and the Chronic Oral Disease Burden (latent variable comprising caries, bleeding on probing, probing depth ≥ 4 mm, clinical attachment level ≥ 3 mm, and visible plaque index ≥ 15%). Socioeconomic Inequalities influencing the Behavioral Risk Factors (latent variable formed by added sugar, smoking, and alcohol) were analyzed using structural equation modeling. (3) Results: Socioeconomic Inequalities were associated with the Chronic Oral Disease Burden [Standardized Coefficient (SC) = 0.222, p < 0.001]. Behavioral Risk Factors were associated with increased Chronic Oral Disease Burden (SC = 0.103; p = 0.013). Obesity was associated with the Insulin Resistance Phenotype (SC = 0.072; p < 0.001) and the Chronic Oral Disease Burden (SC = 0.066; p = 0.005). The Insulin Resistance Phenotype and the Chronic Oral Disease Burden were associated (SC = 0.053; p = 0.032). (4) Conclusion: The grouping of obesity and early events of diabetes with caries and periodontitis call for a syndemic approach in adolescence. |
format | Online Article Text |
id | pubmed-10458482 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104584822023-08-27 Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework Ladeira, Lorena Lúcia Costa Nascimento, Gustavo Giacomelli Leite, Fábio Renato Manzolli Alves-Costa, Silas Barbosa, Janaína Maiana Abreu Alves, Claudia Maria Coelho Thomaz, Erika Barbara Abreu Fonseca Batista, Rosangela Fernandes Lucena Ribeiro, Cecilia Claudia Costa Nutrients Article (1) Background: To investigate the grouping of obesity and insulin resistance with caries and periodontitis from a syndemic perspective through pathways of socioeconomic inequalities, smoking, alcohol, and high sugar consumption in adolescence. (2) Methods: The population-based RPS Cohort study, São Luís, Brazil, in ages 18–19 years (n = 2515) was used. The outcomes were the grouping of pbesity and Insulin Resistance Phenotype (latent variable formed by Triglycerides/HDL ratio, TyG index, and VLDL) and the Chronic Oral Disease Burden (latent variable comprising caries, bleeding on probing, probing depth ≥ 4 mm, clinical attachment level ≥ 3 mm, and visible plaque index ≥ 15%). Socioeconomic Inequalities influencing the Behavioral Risk Factors (latent variable formed by added sugar, smoking, and alcohol) were analyzed using structural equation modeling. (3) Results: Socioeconomic Inequalities were associated with the Chronic Oral Disease Burden [Standardized Coefficient (SC) = 0.222, p < 0.001]. Behavioral Risk Factors were associated with increased Chronic Oral Disease Burden (SC = 0.103; p = 0.013). Obesity was associated with the Insulin Resistance Phenotype (SC = 0.072; p < 0.001) and the Chronic Oral Disease Burden (SC = 0.066; p = 0.005). The Insulin Resistance Phenotype and the Chronic Oral Disease Burden were associated (SC = 0.053; p = 0.032). (4) Conclusion: The grouping of obesity and early events of diabetes with caries and periodontitis call for a syndemic approach in adolescence. MDPI 2023-08-09 /pmc/articles/PMC10458482/ /pubmed/37630703 http://dx.doi.org/10.3390/nu15163512 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ladeira, Lorena Lúcia Costa Nascimento, Gustavo Giacomelli Leite, Fábio Renato Manzolli Alves-Costa, Silas Barbosa, Janaína Maiana Abreu Alves, Claudia Maria Coelho Thomaz, Erika Barbara Abreu Fonseca Batista, Rosangela Fernandes Lucena Ribeiro, Cecilia Claudia Costa Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework |
title | Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework |
title_full | Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework |
title_fullStr | Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework |
title_full_unstemmed | Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework |
title_short | Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework |
title_sort | obesity, insulin resistance, caries, and periodontitis: syndemic framework |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458482/ https://www.ncbi.nlm.nih.gov/pubmed/37630703 http://dx.doi.org/10.3390/nu15163512 |
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