Selective Functionalization of Carbonyl Closo-Decaborate [2-B(10)H(9)CO](−) with Building Block Properties via Grignard Reagents

A green, fast and selective approach for the synthesis of mono-substituted closo-decaborate derivatives [2-B(10)H(9)COR](2−) has been established via a nucleophilic addition reaction between the carbonyl derivative of closo-decaborate [2-B(10)H(9)CO](−) and the corresponding Grignard reagent RMgX, w...

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Detalles Bibliográficos
Autores principales: Mahfouz, Nadine, Abi-Ghaida, Fatima, Kotob, Wael, Mehdi, Ahmad, Naoufal, Daoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458521/
https://www.ncbi.nlm.nih.gov/pubmed/37630327
http://dx.doi.org/10.3390/molecules28166076
Descripción
Sumario:A green, fast and selective approach for the synthesis of mono-substituted closo-decaborate derivatives [2-B(10)H(9)COR](2−) has been established via a nucleophilic addition reaction between the carbonyl derivative of closo-decaborate [2-B(10)H(9)CO](−) and the corresponding Grignard reagent RMgX, where R is the ethyl, iso-propyl, pentyl, allyl, vinyl and propynyl groups. This approach is accomplished under mild conditions with 70–80% yields. The significance of these derivative is their ability to constitute building blocks for polymeric integration via the allyl, vinyl and propynyl substituents. All products were characterized by (11)B, (1)H and (13)C NMR, elemental analysis and mass spectrometry.

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