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Synthesis and Evaluation of ePSMA-DM1: A New Theranostic Small-Molecule Drug Conjugate (T-SMDC) for Prostate Cancer

Small-molecule drug conjugates (SMDCs) are compounds in which a therapeutic payload is conjugated to a targeting vector, for specific delivery to the tumor site. This promising approach can be translated to the treatment of prostate cancer by selecting a targeting vector which binds to the prostate-...

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Detalles Bibliográficos
Autores principales: Murce, Erika, Spaan, Evelien, Beekman, Savanne, van den Brink, Lilian, Handula, Maryana, Stuurman, Debra, de Ridder, Corrina, Dalm, Simone U., Seimbille, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458530/
https://www.ncbi.nlm.nih.gov/pubmed/37630990
http://dx.doi.org/10.3390/ph16081072